During these years (1997-2000) in the research area of annonaceous acetogenins 5 natural products and a number of chiral-pure analogs of annonaceous acetogenins have been synthesized using sugars as the starting materials. Their high activity and selectivity against cell line of colon tumor and a relationship between activity and configuration have been found too. In the respect of inhibitor of sialidase two new methodologies for the synthesis of chiral-pure 3-deoxy-ulosonic acid using hetero-Diels-Alder reaction or asymmetric propargylation as the key reaction were developed. On the topic of anti-leukemia marine natural product clavulactone a synthetic method based on the free radical cyclization and starting from sugar has been developed. In other title of PKC inhibited agent sphingosine a new synthetic route with SN2' as the key reaction has also been disclosed.

項目期間（1997-2000）在番荔枝內(nèi)酯方面從糖出發(fā)合成了五個天然產(chǎn)物和一批手性純的類似物，它們對腸癌細胞有很高的活性和選擇性，并與構(gòu)型有關(guān)黄网占在线；在唾液酸酶抑制劑方面發(fā)展了二類全新手性純高碳糖的合成方法－雜原子D－A反應或丙炔基不對稱加成為關(guān)鍵的反應能看av的网站；抗白血病海洋天然產(chǎn)物群柱蟲內(nèi)酯方面研究了由糖出發(fā)和自由基環(huán)化反應的合成方法；對PKC 起抑制作用的鞘氨醇方面也開創(chuàng)了新的合成途徑－由糖出發(fā)并以SN2'反應為關(guān)鍵反應免费一级a片在线播放视频。

Annonaceous acetogenins are natural compoundsisolated so far only from Annonaceae and showed potential as anticancer,immunosuppressive, and pesticidal agents.

Tonkinecin是一個具C5羥基37個碳的單四氫呋喃環(huán)番荔枝內(nèi)酯化合物免费看av的在线网站，它對人類腫瘤細胞如肝細胞瘤、胃癌等強烈細胞毒性黄色三级人人操。

Objective To investigate the effects of annonaceous acetogenin on proliferation and apoptosis in Raji cells and its mechanism.

目的 研究番荔枝內(nèi)酯對體外人淋巴瘤Raji細胞體外增殖和凋亡的影響及其可能機制九九激情视频在线看。

Objective To observe the inhibitory action of annonaceous acetogenins AS-4 on human liver cancer cell line HepG2 in vitro.

目的研究番荔枝內(nèi)酯AS-4在體外對人肝癌細胞株HepG2生長的抑制作用。

Objective To observe the inhibitory action of annonaceous acetogenins AS-4 on human liver cancer cell line HepG2 in vitro.

目的 研究番荔枝內(nèi)酯AS-4在體外對人肝癌細胞株HepG2生長的抑制作用日韩激情中文字幕视频在线。

annonaceous：番荔枝科的

annomination | 類語重疊 | annonaceous | 番荔枝科的 | annotate | 注釋, 評注