Objective: To investigate the expression of P53欧美黃片AAAAAA色、BCL2 and BAX in 70 transitional cell carcinomata of bladder and 10 cystitis.

目的 ：探討與細胞凋亡關(guān)系最為密切的三個基因 P5 3、BCL2及 BAX在膀胱移行細胞癌中的表達與其病理分級及預后的關(guān)系亚洲欧美自拍第一页。

It is intimately involved in spindle formation and chromosome segregation during mitosis. Now, the over-expression of PLK1 has been found in various primary carcinomata, and indicated the probability of PLK1 as a new tumor marker.

近年來av资源免费，研究發(fā)現(xiàn)PLK1（polo-like kinase 1）基因在有絲分裂過程中起重要的調(diào)節(jié)功能，并且在多種的人類腫瘤包括肺癌中發(fā)現(xiàn)PLK1基因表達升高亚洲无码视频亚洲人的网站，提示PLKl的增長表達在細胞的增殖中起重要作用操学生妹视频在线观看，預示PLK1可能是一個新的腫瘤標記物。

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文題名反義與反基因寡核苷酸及其萘二酰亞胺偶聯(lián)物對靶基因表達的抑制作用研究副題名外文題名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 論文作者李軍生導師張元興魏東芝教授學科專業(yè)生物化工研究領(lǐng)域\研究方向生物化學與分子生物學學位級別博士學位授予單位華東理工大學學位授予日期2001 論文頁碼總數(shù)106頁關(guān)鍵詞基因表達基因治療反義寡核苷酸反基因寡核苷酸核酸館藏號BSLW /2001 /Q78 /264 針對人表皮癌抗阿霉素細胞株（KB-A-1）的多藥抗藥性問題高h一区，本文從反義核酸和反基因核酸角度日日插日日操，通過MTT法檢測細胞生長情況，ELISA法檢測基因表達產(chǎn)物P-gp表達水平的變化先锋影音资源AV网站，對寡核苷酸抑制腫瘤細胞MDR1基因表達的機制進行了探討久久精品国产福利国产秒。