White nails, found in the accident and loss of blood and shock; chronic diseases are found in anemia, hookworm disease, chronic gastrointestinal bleeding, tuberculosis hemoptysis, pulmonary heart disease and so on; as if a nail white glass, while the characteristics of liver cirrhosis; nail change White, thin, soft, was particularly prevalent in the chronic wasting disease; yellow nail is the lack of vitamin E hypothyroidism, nephrotic syndrome, and other symbolic; gray nails are often suffering from Onychomycosis, a performance for the initial stage next to the itching, Following the nail is deformed, but was dull gray; purple nails with a small red thorn is caused by hypoxia, indicating pulmonary heart disease; nail half red, half white (commonly known as a yin and yang) is not a manifestation of renal function; white nail Flocculation, or white, zinc deficiency may be, anemia or gastrointestinal system is sick; nail spots is the emergence of the performance of the poisoning; redness around the nail, mostly lupus erythematosus and in patients with dermatomyositis; nail root A blue and a half months is a reflection of peripheral circulation; obvious red nails, is the performance of heart failure; a clear and a half months, prompted the digestive system function better absorption; On the other hand, there is no clearance on a narrow or a half months, that is, Tip of the digestive system problems.

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After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

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Immunosuppression after renal transplantation seems to enhance viral replication and increase the risk of developing cirrhosis and hepatocellular carcinoma.

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