No1 Guyu could improve proliferation and differentiation of skeletogenous cells, which relative to dosage of drug.

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Methods: The skeletogenous cells which were taken from cranial bones of SD rats cultivated, and were devided into 4 groups, the culture solution of which were added in order rabbit serum without No1 Guyu, and with No1 Guyu of density 12.5g/Kg, 25g/Kg, 50g/Kg.

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