In our research on study chemical reaction of active methylene compounds and brom-acetophenone. Because of brom-acetophenone is compound that contain carbonyl and halogen ,which will take place electrophilic substitution and nucleophilic addition. When active methylene compounds are ethyl acetoacetate and β-diketone, controlling reaction condition, we have found that mono-substitution's production and di-substitution's. production is isolated; active methylene compounds are acetoacetanilide and acetoacetanilide derivate, pyrrolidin-2-one derivants were obtained by substitution and close-ring reaction .but there is no report about it.

本文是讓活潑亞甲基類(lèi)化合物與溴代苯乙酮發(fā)生化學(xué)反應(yīng)222www免费观看，由于溴代苯乙酮是含有羰基的鹵代烴結(jié)構(gòu)在线强奸，它可以發(fā)生親電取代和親核加成反應(yīng)，當(dāng)活潑亞甲基類(lèi)化合物為乙酰乙酸乙酯和β-二酮時(shí)午夜亚洲视频，控制反應(yīng)條件可以發(fā)生單取代和雙取代兩種產(chǎn)物欧美日韩福利视频一区；當(dāng)活潑亞甲基類(lèi)化合物為乙酰乙酰芳胺類(lèi)化合物來(lái)反應(yīng)時(shí)，溴代苯乙酮中的羰基與氨基會(huì)發(fā)生分子內(nèi)的關(guān)環(huán)反應(yīng)生成吡咯烷-2-酮衍生物超碰97公开免费在线，這在以前的研究中是沒(méi)有發(fā)現(xiàn)的热99在线精品免费观看高清。

A selective and mild PS-DIB/ionic-liquid immobilized 2, 2, 6, 6-tetramethyl-piperidin-4-ol-N-oxyl catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via the iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TeMPO catalyst, 4-(2, 2, 6, 6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from TeMPO and 1, 4-dibromobutane.

將聚苯乙烯樹(shù)脂先碘化再乙酰基化，制得了負(fù)載型二乙酰氧碘苯作為氧化劑九七人人操。2国产初高中精品网， 2， 6国产精品免费高清在线观看， 6-四甲基－N-氧自由基哌啶醇與1鲁在线视频， 4-二溴丁烷反應(yīng)生成4-溴丁氧基－2， 2日韩伊人网， 6色色色8， 6-四甲基－哌啶－1-氧化物，再與N-甲基咪唑發(fā)生季銨化反應(yīng)人人操一区，生成的溴化季銨鹽與四氟硼酸鈉進(jìn)行離子交換制得氟硼酸型2亚洲操大逼综合网， 2， 6日韩在线精品色欲视频观看免费网站， 6-四甲基－N-氧自由基哌啶負(fù)載離子液體免费看黄色网站视频。

Ethoxycarbonyl-4,5-dimethyl-pyrrole (7) was prepared from ethylacetoacetate, ethyl formate and methyl ethyl ketone via oximination, Claisen condensation, and reductive condensation. The bromization of compound 7 gave 2-ethoxycarbonyl-3-bromo-4,5-dimethyl-pyrrole(8), which could be transferred to 2-ethoxy-carbonyl-3-brome-4-methyl-5-formyl-pyrrole (9) by the formolation.

由乙酰乙酸乙酯、甲酸乙酯及丁酮等原料經(jīng)過(guò)肟化一a黄色视频a、Claisen縮合啦啦啦www在线下载、還原縮合成環(huán)得到2-乙氧羰基－4，5-二甲基－吡咯(7)人妻论坛，溴化生成2-乙氧羰基－3-溴4丁香婷婷开心激情深爱五月，5-二甲基－吡咯(8)，最后經(jīng)過(guò)甲跷逶露∠懔伦酆希化反應(yīng)得到目標(biāo)產(chǎn)物2-乙氧羰基－3-溴－4-甲基－5-甲趼胰寺资悠狄患叮基－吡咯(9)。

A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.

本發(fā)明涉及一種制備對(duì)氟－2－(2－甲基－3－氧丙基)－4－氧－N国产精品免费久久久久电影网，3－二苯基－苯丁酰胺(1)的方法黄色视频热播无码，其包括以下步驟：新制的苯乙酰氯與氟苯在AlCl3催化下進(jìn)行Friedle－Craft酰化反應(yīng)久热精品视频，得到對(duì)4－氟－苯基芐基酮(4)国产免费午夜福利天堂AV；化合物(4)在少量AlCl3催化下進(jìn)行羰基α位溴化，得到α－溴－4－氟－苯基芐基酮(5)欧美日韩国产成A免费网站；然后(3)異丁酰乙酰苯胺在乙醇鈉作用下與化合物(5)進(jìn)行縮合。

In order to decrease toxicities of retinods and enhance pharmacal effects and gain the relative derivatives with better curing effect and selectivity, structures of retinoic acids were modified by inducing glycosyl groups in this paper.

方法一是在氫氧化鉀存在下欧美乱伦视频二区，以4-二甲氨基吡啶做相轉(zhuǎn)移催化劑免费观黄色视频，將溴代-O-乙酰基葡萄糖(5a)在线产国产、溴代-O-乙趺夥压鶤片一级；咎?5b)、溴代-O-乙酰基乳糖(5c)和溴代-O-乙跖访谰纷酆闲跃镁糜霸海基麥芽糖(5d)分別與異維A酸反應(yīng)制得1-O-異維A酰-乙豕蘸纷耘腁V；鶈翁?6a，6b)和1-O-異維A酰-乙趼芈腋咔迕夥咽悠倒劭碅A片；?6c高清无码免费在线视频专区，6d)，收率為53～65%欧美另类福利视频。

The famciclovir was synthesized from purine by a series of steps by Acylation, Decarboxylation, Reduction ,and so on; Derivatives of these intermediates is described from the 6-chloro- 9H- purin-2-amine as raw materials in different conditions when the iodine and bromide were synthesized with the addition of two intermediate 6-bromo-9H-purin-2-amine and 6-iodo-9H-purin-2-amine; There is elaborated from the main part of a acetophenone, urineaminohydrochloride, phenylhydrazine, ethyl acetoacetate as raw material through a series of reactions to synthetic 3-phenyl-4-formylphenyl pyrazole and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-aldehyde two pyrazole aldehyde, and then with 2-amino-6-chlorine-9-(2-methicillin-oxo-co-methyl-4-yl) purine reaction of the two new pyrazole purine Schiff bases.

本論文主是采用以鳥(niǎo)嘌呤為原料欧美一级a大片在线观看，經(jīng)過(guò)一系列的酰基化黄色视频一区二区三区在线看，脫羧精品人成视频免费国产，還原等反應(yīng)作用下最終得到了產(chǎn)物2-氨基-9-(4-乙酰氧基-3-乙酰氧基甲基丁基)嘌呤；其中的中間體衍生物主要是闡述從以2-氨基-6-氯鳥(niǎo)嘌呤為原料通過(guò)在不同的條件下進(jìn)行溴代與碘代分別合成了另外兩種中間體2-氨基-6-溴鳥(niǎo)嘌呤及2-氨基-6-碘鳥(niǎo)嘌呤欧美黑人日韩一级视频在线观看免费；還有一部分主要是闡述從以苯乙酮欧美久草，鹽酸氨基脲，苯肼成年欧美1313www色，乙酰乙酸乙酯為原料通過(guò)一系列的反應(yīng)先合成3-苯基-4-醛基吡唑及5-氯-3-甲基-1-苯基-1H-吡唑-4-甲醛這兩個(gè)吡唑醛别揉我奶头视频一区，然后再與2-氨基-6-氯-9-(2-甲氧羰基丁酸甲酯-4-基)嘌呤反應(yīng)得到了兩個(gè)新型的吡唑嘌呤席夫堿

It is found that when the molar ratio of sulphoxide,pyridine and acetyl bromide is 1∶0.6∶0.4,the catalytic effect on the ring-enlargment is the best,and the yield and purity of the final product can reach 76% and 97% respectively at a pH of 1.8 in toluene under refluxing for about 3.5h.

通過(guò)正交實(shí)驗(yàn)可得出以下結(jié)論：當(dāng)N，N′-雙脲-亞砜為2.5∶1超碰91欧美，乙酰溴-亞砜為0.4∶1igao视频在线观看播放，吡啶-乙酰溴為1.5∶1，回流時(shí)間為3.5hA级黄片小视频免费观看，酸化pH值為1.8時(shí)欧美一级裸体视频在线观看，擴(kuò)環(huán)反應(yīng)結(jié)果最好，總收率可達(dá)76%jizzjizz日本高清视频免费，純度97%以上电影一区小说区偷拍区。

For example, pulverized wood samples can be treated with acetyl bromide in acetic acid, and the absorbance of the resulting solution at 280 nm can be compared with the absorbance obtained from known lignin standards.

例如，將木屑樣品在乙酸環(huán)境下與乙酰溴進(jìn)行反應(yīng)久久美女夫妻性爱真实视频，再將280納摩爾所得溶液的吸收率與已知的木質(zhì)素標(biāo)準(zhǔn)吸收率進(jìn)行比較尤物视频在线网址。

Bromo-5-formyl -3-methylpyrrole is an important intermediate of tolyporohin. On the base of introducing the present research and development of tolypo- rohin and pyrroles ramification at home and abroad, an emphasis was made on synthesis of 2-Bromo-5-formyl -3-methylpyrrole and the technical conditions of all steps, which was described as follows. Diethyl 3,5-dimethylpyrrole-2,4-dicarboxylate was made by nitrification, reduction and cycle of ethyl acetoacetate.

由于2-溴-5-甲酰基-3-甲基吡咯是合成托尼卟吩的重要中間體欧美国产A片免费久久，本文在闡述了當(dāng)前托尼卟吩及吡咯衍生物的國(guó)內(nèi)外研究和開(kāi)發(fā)的基礎(chǔ)上欧美一级爱爱视频一区二区，重點(diǎn)研究了2-溴-5-甲酰基-3-甲基吡咯的合成一级片电影网站，并對(duì)各步反應(yīng)進(jìn)行了工藝研究亚洲最大黄网欧美在线，具體合成步驟如下：本文通過(guò)對(duì)乙酰乙酸乙酯的亞硝化、還原最黄视频一区二区三区免费观看、成環(huán)黄色网站日韩，反應(yīng)生成吡咯單環(huán)衍生物2久久国产精品高跟丝袜美腿，4-二乙氧羰基-3，5-二甲基吡咯50,60,70老熟妇视频。

The effect of chloroacetyl chloride and bromoacetyl bromide on yields of intermediates and nitrazepam was compared.

比較了氯乙酰氯和溴乙酰溴對(duì)中間體及硝基安定收率的影響欧美激情1。

acetyl bromide：乙酰溴

aceturic acid 乙酰甘氨酸 | acetyl bromide 乙酰溴 | acetyl chloride 乙酰氯

acetyl bromide：溴化乙酰

過(guò)氧化苯乙酰 acetyl benzoyl peroxide | 溴化乙酰 acetyl bromide | 氯化乙酰 acetyl chloride

acetobromanilide：[醫(yī)] 溴乙酰苯胺

1233acetobromal[醫(yī)] 乙酰[基]溴醛 | 1234acetobromamide[化] N-溴乙酰胺; 乙酰溴胺 | 1235acetobromanilide[醫(yī)] 溴乙酰苯胺

aceturic acid：乙酰甘氨酸

acetoxylation 乙酸化 | aceturic acid 乙酰甘氨酸 | acetyl bromide 乙酰溴

bromacetanilide：乙酰溴苯胺

broma | 去油可可豆, 任何供咀嚼的固體食物 | bromacetanilide | 乙酰溴苯胺 | bromacetate | 溴乙酸鹽

Ethanoyl：乙跖访廊蘸肥悠狄磺谙呖矗基

ethanol乙醇 | ethanoyl乙趸菩允悠翟谙撸基 | ethanoyl bromide乙酰溴

ethanoyl bromide：乙酰溴

ethanoyl乙酰基 | ethanoyl bromide乙酰溴 | ethanoyl chloride乙酰氯

ethanoyl chloride：乙酰氯

ethanoyl bromide乙酰溴 | ethanoyl chloride乙酰氯 | ethanoyl iodide乙酰碘

ethanoyl bromide; acetyl bromide：溴化乙酰;乙酰溴

乙醇 ethanol | 溴化乙酰;乙酰溴 ethanoyl bromide; acetyl bromide | 氯化乙酰;乙酰氯 ethanoyl chloride; acetyl chloride

ethanoyl chloride; acetyl chloride：氯化乙酰;乙酰氯

溴化乙酰;乙酰溴 ethanoyl bromide; acetyl bromide | 氯化乙酰;乙酰氯 ethanoyl chloride; acetyl chloride | 氟化乙酰;乙酰氟 ethanoyl fluoride; acetyl fluoride