Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶為起始原料国产精品亚洲码精品，經(jīng)醚化www18岁、硝基還原得到3-氯－4-（吡啶－2-甲氧基）苯胺亚洲一区精品劲爆儿视频，3-氯－4-（吡啶－2-甲氧基）苯胺與3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反應(yīng)得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉操操操操操操人人人人人操，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保護基后欧美一级婬片A片护士，與-4-二甲氨基－2-丁烯酰氯經(jīng)酰化反應(yīng)得到ner-atinib。

Diamino-3,5-dinitropyridine and 2,6-diamino-3,5-dinitropyridine-1-oxide was reacted with aqueous ammonia and KMnO4 under different conditions. Substitutions in the 4 position to the nitro group were obtained with high yields: 2,4,6-triamino-3,5-dinitropyridine (81.5%) and 2,4,6-triamino-3,5-dinitropyridine-1-oxide (85.4%).

以氨水為胺化劑婷婷在线综合，KMnO4為氧化劑亚洲欧美日本一区二区综合，在不同反應(yīng)條件下實現(xiàn)2，6-二氨基-3亚洲欧美性爱片，5-二硝基吡啶和2中文字幕中日韩欧美一区，6-二氨基-3，5-二硝基吡啶-1-氧化物4位的氧化胺化反應(yīng)中文字幕第几页，目標化合物2特级欧美AAAAAA视，4，6-三氨基-3精品一级黄色视频国产片一区，5-二硝基吡啶和2日韩黄色网不卡网站，4，6-三氨基-3jlzz大全高潮多水老师，5-二硝基吡啶-1-氧化物的收率分別達到81.5%和85.4%A片免费观看在线播放。

Many of the aza quinazolines have showed potent activity, such as pyrido[2,3-d]pyrimidine, pyrido [3,2-d]pyrimidine, pyrido[4,3-d]pyrimidine, pyrido[3,4-d]pyrimidine, and pyrimido [5,4-d]pyrimidine. Moreover, the compounds that the benzene in quinazoline ring was substituted by five-member rings, such as pyrrolo[2,3-d]pyrimidine, pyrazolo[3,4-d]pyrimidine, can also inhibit the EGFR and show bright prospects.

然而喹唑啉環(huán)并非EGFR抑制劑所必須的，在隨后的研究中一级特黄aa毛片大片在线，人們發(fā)現(xiàn)許多氮雜喹唑啉類也有很好的活性亚洲黄色12级视频，如吡啶并[2，3-d]嘧啶類亚洲毛片在线播放、吡啶并[3国内黄片免费看，2-d]嘧啶類、吡啶并[4国产亚洲真人视频在线观看，3-d]嘧啶類欧美性爱肛交在线观看、吡啶并[3，4-d]嘧啶類黄片久久免费看aV、嘧啶并[5强奸人人操，4-d]嘧啶類，也就是在喹唑啉環(huán)的5A毛片毛片看免费一A毛片，6国内精品久久久麻豆精品，7，8-位都可以氮雜欧美一级人人曹，且都有活性国产三级片插逼视频。

Starting from pentachloropyridine, intermediate product 2,3,5,6-tetrachloropyridine was prepared by reduction with zinc dust .

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In order to solve the backward electron transfer problem, 9 kinds of rhenium bipyridyl photosensitive dyes with different electron donating groups on the p or m-position of the pyridine rings, 2 kinds of rhenium bipyridyl and 2 kinds of ruthenium tris-bipyridyl photosensitive dyes with two tyrosine ethyl ester groups on the bipyridyl rings were designed and synthesized.

本文針對該類太陽能電池中存在的電子回傳問題，設(shè)計合成了在吡啶配體的間位和對位帶有不同供電基團的9種錸聯(lián)吡啶光敏染料国产特黄特色视频网站，在聯(lián)吡啶配體上帶有兩個酪氨酸基團的2種錸聯(lián)吡啶和2種釕三聯(lián)吡啶光敏染料欧美中韩一区二区。

In the synthesis of 2,3,5-trichloropyridine, 2-aminopyridine was firstly chloridized to 2-amino-3, 5-dichloropyridine, and then sodium nitrite solution was added with the existence of hydrogen chloride to diazotize the 2-amino-3,5-dichloropyridine.

在2，3午夜在线色呦呦，5-三氯吡啶的合成上人妻人操人人操人人插，首先通過對2-氨基吡啶的氯化生成2-氨基-3，5-二氯吡啶亚洲网站黄色，然后再有鹽酸存在條件下加亞硝酸鈉溶液重氮化后日韩成人精品视频自拍，發(fā)生桑德邁爾反應(yīng)生成2，3亚洲欧美人成人综合在线播放，5-三氯吡啶和3亚洲一级毛片免费看，5-二氯吡啶-2-酮的混合物，最后用氯化亞砜進行再次氯化久久停黄色网站，經(jīng)處理得到產(chǎn)品2国产精品一级黄录像，3，5-三氯吡啶国产丝袜视频在线播放一区。

Three novel rigid compounds 3, 6-bis[2-(4-pyridylethenyl]-9-ethylcarbazole (L~1), 3,6-bis[2-(2-pyridyl)ethenyl]-9-ethylcarbazole (L~2), 3,6-bis[2-(4-pyridyl)ethenyl]-9 -ethylpyridylcarbazole (L~3) were successfully synthesized by Heck reaction, which were fully characterized by elemental analyses, NMR, MS, IR spectra and single X-ray diffraction analysis.

利用Heck偶聯(lián)反應(yīng)小黄片在线播放情侣，成功地合成了三種新型剛性的吡啶基咔唑類化合物：3，6-二[2-(4-吡啶基)乙烯基]-9-乙基咔唑(L~1)黄片zaixian免费，326uuu亚洲日韩欧美，6-二[2-(2-吡啶基)乙烯基]-9-乙基咔唑(L~2)和3，6-二[2-(4-吡啶基)吡啶基]-9-乙基吡啶基咔唑(L~3)www.av天堂2020，通過元素分析亚洲√a无码作爱、核磁共振譜、質(zhì)譜先锋影音最新av资源网址、紅外光譜和單晶X-射線衍射等分析手段確證了它們的結(jié)構(gòu)国产青榴视频A片在线观看不卡成。

The molecular designs and synthesis of triarylamine-based picolinic acid derivatives used as ancillary ligands, and their cyclometalated iridium complexes used as red-and green-emitters, as well as optoelectronics properites of these compounds were investigated in order to solve current problems of organic/polymeric electroluminescent materials and devices.

本論文針對目前有機/聚合物電致磷光材料和器件存在的問題，開展了新型三芳胺吡啶羧酸類輔助配體及其紅光和綠光環(huán)金屬銥配合物電致磷光材料的分子設(shè)計亚洲性爱视频网址、合成和光電性能研究欧美刺激a片影院，主要包括：(1)設(shè)計、合成了三種新型的三芳胺吡啶羧酸類雙齒陰離子型輔助配體26uuu欧美日韩国产；(2)以三芳胺吡啶羧酸衍生物作為雙齒陰離子型輔助配體A级黄色片在线免费观看，合成得到了兩個系列的紅光和綠光環(huán)金屬銥配合物A片vi视频；(3)研究了三芳胺吡啶羧酸類輔助配體分子結(jié)構(gòu)對環(huán)金屬配合物的紫外吸收和光致發(fā)光性能的影響；(4)以環(huán)金屬配合物為客體美女裸体扒开尿口桶到爽动态图，聚芴和惡二唑衍生物為主體精品国产亚洲，制作了聚合物電磷光器件，研究了含三芳胺吡啶羧酸類輔助配體久久riAV一区二区三区、環(huán)金屬配合物客體材料和聚合物主體材料等分子結(jié)構(gòu)對電致發(fā)光性能的影響成视频年人黄网站免费视频高潮。

Based on the research and development of synthesis of halogenated pyridines the paper chose the electrochemical reduction as a research direction, and to 3,4,5,6–tetrachloropicolinic acid, pentachloropyridine, 3,4,5,6-tetrachloro-2-trichloromethylpyridine for raw materials, the reduction behavior on silver and carbon -containing silver electrode was mainly studied.

全鹵吡啶脫氯是鹵代吡啶類化合物合成的新嘗試，本文在國內(nèi)外鹵代吡啶合成研究的基礎(chǔ)上99re在线观看这里只有精品9，選擇了以電化學(xué)還原作為研究方向能在线看av的网站，以3，4黄色免费在线视频网址，5www狠狠干，6-四氯吡啶甲酸、五氯吡啶人人色人人模、3破苞视频，4，5欧美福利大片，6-四氯-2-三氯甲基吡啶為原料中文字幕无码视频专区免费视频，主要研究了其在銀和碳載銀電極上的還原行為。

The effects of pyridine substitutive derivations on the metabolic pathway of Blakeslea Trispora, were studied such as 2,6-dimethylpyridine,2,5-dimethylpyridine, 2-amino-6-methylpyridine and tobacco dust which contains mainly 3-pyridine substitutive derivation.

主要考察了吡啶衍生物如2综合激情图区，6-二甲基吡啶3p无码视频、2，5-二甲基吡啶欧美熟妇A片一级人A片一级、2-氨基-6-甲基吡啶及煙草廢棄物（主要成分為3-吡啶基衍生物）對三孢布拉氏霉菌代謝途徑的影響一级操屄视频。

picoline：甲基吡啶 皮考啉

picolinamide 吡啶酰胺 | picoline 甲基吡啶 皮考啉 | picolinicacid 甲基吡啶酸

pyridine alkaloid：吡啶生物鹼 吡啶生物堿

pyranose 吡喃糖 吡喃糖 | pyridine alkaloid 吡啶生物鹼 吡啶生物堿 | pyrogen 熱原 熱原

quinoline：喹啉;苯并吡啶

對苯二酚;氫醌 quinol; hydroquinone | 喹啉;苯并吡啶 quinoline | 喹啉酸;2,3-吡啶二甲酸 quinolinic acid; pyridine-2,3-dicarboxylic acid

sulfapyridine calcium：磺胺吡啶鈣

sulfapyrazine sodium 磺胺吡嗪鈉 | sulfapyridine calcium 磺胺吡啶鈣 | sulfapyridine sodium 磺胺吡啶鈉

sulfapyridine sodium：磺胺吡啶鈉

sulfapyridine calcium 磺胺吡啶鈣 | sulfapyridine sodium 磺胺吡啶鈉 | sulfasuccinamide sodium 磺胺琥珀酰胺鈉

pyridinium fluoroborate：氟硼酸吡啶

"pyridinium compound","吡啶基化合物" | "pyridinium fluoroborate","氟硼酸吡啶" | "pyridylethylation","吡啶乙基化"

pyridine monocarboxylic acid：吡啶一羧酸

pyridine dye 吡啶染料 | pyridine monocarboxylic acid 吡啶一羧酸 | pyridine monosulfonic acid 吡啶一磺酸

pyridine monosulfonic acid：吡啶一磺酸

pyridine monocarboxylic acid 吡啶一羧酸 | pyridine monosulfonic acid 吡啶一磺酸 | pyridine perchlorate 高氯酸吡啶

pyridinium compound：吡啶基化合物

"pyridine","吡啶" | "pyridinium compound","吡啶基化合物" | "pyridinium fluoroborate","氟硼酸吡啶"

pyridone：吡啶酮;羥基吡啶

pyridinoprotein enzyme 吡啶蛋白酶 | pyridone 吡啶酮;羥基吡啶 | pyridoxal 吡哆醛;維生素 B6