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The cytotoxicity of these compounds were valuated by MTT and SRB methods using three cancer cell lines: HL-60, A-549, P-388. Cyclo-shikonin, and cyclo-alkannin have high cytotoxicity against HL-60.The chiral center of side chain has no effect on their activity. 2- 1-(Acetyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (105) has strong inhibition effect on P-388 cells. 2- 1-(isooctyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (108) and 2- 1-(2-furoyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (112) have high inhibition on A-549.Shikonin (1), alkannin (2), and their derivatives have the structural features of a planar chromophores and short side chain. We examined the ability to inhibit the telomerase.

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The 'permanent truth' is close to Russell's 'apriority' of induction. However, in my opinion, this kind of permanent truth or apriority doesn't have any important sense since the principle of anti-induction, i.e., ' if a t 1 — b t b ,……, a t n — b t n then probably A ?

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So, for example,'A' is a character constant; in the ASCII character set its value is 65, the internal representation of the character A.

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Though comparing Canny operator and center B spline dyadic wavelet, the following conclusion is proven in this dissertation: a Center B spline function has tight support and Canny operator hasn't. b Center B spline function asymptotic convergence to Gaussian function and the derivative of Center B spline function asymptotic convergence to Canny operator. c The derivative of fourth order center spline B function is more suitable as a optimal edge detector than Canny operator. d Center B spline function can balance the smoothing and approximation of original data, and the fourth center B spline function is the only optimal solution of two order smoothing problem. e The error between the valve of time-frequency uncertainty of the fourth center B spline function and the lower bound of time-frequency uncertainty does not exceed 0.143% of the lower bound. f The derivative of center spline B function can construct a stability dyadic wavelet and can give a fast algorithm for multiscale edge detection, but Canny operator can do neither.

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So, we combine CobraNet audio network technology, data transmitting technology, MCU technology and FPGA technology to develop interface and program of MCU, controlling PCB board, A/D converter PCB board, D/A converter PCB board, digital audio receive PCB board. At last, we construct a audio network and test it's performances.

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