The allelic diversity in terms of number of alleles per locus and expected heterozygosities in cultured populations N=8.0-9.4, H(subscript e=0.754-0.787 was considerably lower than that found in the wild populations N=11.3-15.0, H(subscript e=0.821-0.866. Allele distributions at all seven microsatellites indicated that the cultured populations lost some rare alleles belonging to wild populations. The small number and the biased sex ratio of abalone for hatchery broodstock might be responsible for the remarkable reduction of genetic variation in the studied populations.

結(jié)果表明强奸视频的网站，從等位基因數(shù)與雜合度上分析超碰国产人人洗澡人人操，養(yǎng)殖群體(N=8.0~9.4伊人色综合狠狠热AV电影， H=0.754~0.787)遺傳多樣性顯著低于野生群體N=11.3~15.0人人操性视， H(下標(biāo) e=0.821~0.866国产13一14娇小性；等位基因頻率分布揭示出野生群體中一些稀有等位基因在養(yǎng)殖群體中有所丟失自拍偷拍精品视频网；親鮑選用數(shù)量少與性別比例不均衡可能是產(chǎn)生養(yǎng)殖群體中遺傳多樣性顯著減少的原因。

In 110 Xinjiang unrelated healthy Uygur subjects, 27 alleles were detected in HLA-B loci. Of them, B * 35 and B * 51 were the most common alleles with an allele frequency of 0.1136 and 0.1136, respectively; while B * 41, B * 56 and B * 78 were the rare alleles with a frequency of 0.0045, 0.0045 and 0.0091, respectively. Frequencies of "Caucasoid origin" HLA alleles such as B * 08, B * 35 and B * 50 in Xinjiang Uygurs were higher than other ethnic groups in China.

在維吾爾族樣品中共檢出27個等位基因日韩欧美一级视频免费播放，其中高頻率的等位基因?yàn)锽*35(0.1136)和B*51(0.1136)激情毛片免费看，低頻率的等位基因?yàn)锽*41(0.0045)、B*56(0.0045)和B*78(0.0091)亚洲男人天堂av无码，B*08久久公开免费视频观szs、B*35、B*50等"高加索人"起源的HLA基因在新疆維吾爾族的分布頻率高于國內(nèi)其他民族美女在線免費密月A片視頻，與高加索人種的數(shù)值相當(dāng)亚洲一级精品A片免费视频。

The results showed that:(1) we can mapping quantitative trait locus while estimating the variance component of QTL;(2) granddaughter design is better than daughter design when mapping QTL;(3) it is easy to map a QTL for trait with a high heriability and a large QTL variance contribution;(4) we can estimate the variance component of a QTL by TM-BLUP based on ML method whether the QTL has only 2 alleles or QTL has normal distributed alleles effects;(5) the estimation accuracy of variance component contributed by QTL was improved by using of grand daughter design;(6) the higher the heritability and the QTL variance contribution was, the more accurate estimation of QTL variance component.

結(jié)果表明：（1）采用隨機(jī)QTL效應(yīng)模型和最大似然法，在估計QTL方差組分的同時手机欧美性爱第一页，能夠定位QTL一级A片免费天天噜；（2）孫女設(shè)計與女兒設(shè)計相比，在其它因素相同時美女被c啊啊，容易檢出QTL欧美亚洲日韩国产精品第6页；（3）遺傳力高，QTL方差貢獻(xiàn)較大的性狀可以看被操的网站，QTL檢出的效果優(yōu)于遺傳力低日夲一级片，QTL方差貢獻(xiàn)較小的性狀；（4）無論QTL上有2個等位基因黄片视频A级毛片在线观看，還是QTL上等位基因的效應(yīng)服從正態(tài)分布国产成长精品视频，都可將其看作隨機(jī)效應(yīng)，采用基于TM-BLUP的ML法国产精品自在在线午夜，估計其方差組分和定位QTL亚洲激情视频网；（5）QTL方差組分估計的準(zhǔn)確性，孫女設(shè)計高于女兒設(shè)計A大片黄片视频；（6）遺傳力高的性狀日本女色视频，QTL方差貢獻(xiàn)大的QTL，QTL方差組分估計的準(zhǔn)確性高动漫高潮娇喘抽搐喷水视频。

Methods Fifty pairs of fresh colorectal cancer and homologous normal tissues were genotyped with Identifiler Kit and the mutations generated in cancer tissues were determined. The mutation rates, the numbers of locus matched without identical allele (A0), 1 identical allele (A1), or 2 identical alleles (A2) and the number of total identical alleles IA(subscript n were calculated. Frequency distributions of A0, A1, A2 and IA were compared among CR-N group, unrelated individual pairs and full sibling pairs. Discrimination functions were established for individual identification from tumor tissues with discriminatory analysis.

用Identifiler系統(tǒng)對50對新鮮結(jié)直腸癌組織及其身源正常組織組進(jìn)行STR分型A级黄色网站在线免费观看视频，計算CR-N組中變異STR基因座及全不同基因座數(shù)(A0)、半相同基因座數(shù)(A1)一级毛片免费网站视频中文、全相同基因座數(shù)(A2)和共有等位基因數(shù)IA(下標(biāo) n在线观看视频黄页，比較CR-N組欧洲视频一区二区三区、無關(guān)個體對組和全同胞對組中上述參數(shù)的分布差異，通過判別分析建立判別函數(shù)国产精品亚洲日韩欧美第一页。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

結(jié)果檢出10個家系25例病人及1例癥狀前18歲女孩有MJD基因突變一级a毛片免灵靠看久久精品，CAG三核苷酸重復(fù)73～79次，異常等位基因片段長380～402bp国产原创自拍，均為雜合子黄色视频一区二区观看；正常人CAG三核苷酸重復(fù)18～40次，等位片段長200～270bp一级α片屄，電生理發(fā)現(xiàn)MJD的SCV減慢比MCV明顯欧美精品黄一区，而下肢的MCV、SCV又較上肢明顯操干无码在线视频，BAEP很在线视频无码一二三四区、VEP均有不同程度的潛伏期延長或波的異常；MJD的父親遺傳早于母親男人天堂网站网址，進(jìn)展也較塊91精品国产福利下线，臨床以小腦性共濟(jì)失調(diào)為突出癥狀，其次為構(gòu)音障礙91部精品国产费观、突眼等欧美三级黄色网站，肌肉萎縮僅見于晚期病人；MRI示小腦萎縮較明顯黄色一级免费片，腦干萎縮并不嚴(yán)重十八岁黄片，未見明顯的頸髓萎縮。

A person with a pair of identical alleles for a particular gene is a homozygote; a person with a pair of dissimilar alleles is a heterozygote.

一個人如果帶有某個基因的兩個相同的等位基因26uuuu综合，是純合子9AV在线观看视频；如帶有兩個不相同的等位基因，則為雜合子求国产精品网址。

The frequencies of CCR5delta32,CCR2b-64I,SDF1-3′A alleles in Dai population were 0.0000,0.2130,0.2030,respectively;The frequencies of CCR5delta32,CCR2b-64I,SDF1-3′A alleles in Chingpaw population were 0.000,0.1637,0.1770,respectively.Distributions of the CCR2b-64I,SDF1-3′A alleles among the both populations were in accordance with Hardy-Weinberg equilibrium.No statistical difference was found in the allelic frequencies of both CCR2b-64I and SDF1-3′A between male and female individuals.

結(jié)果表明亚洲一级性交大片，中國傣族景頗族人群中未發(fā)現(xiàn)CCR5△32等位基因突變；傣族CCR2b-64I亚洲一区亚洲二区、SDF1-3′A基因突變頻率分別為0.2130和0.2030日韩偷窥自拍系列视频在线，景頗族CCR2b-64I和SDF1-3′A基因突變頻率分別為0.1637和0.1770；與中國漢族人群相比較超碰在线97在线，傣族和景頗族中SDF1-3′A突變頻率較低（P值分別為0.0322和0.0021）色哟哟哟；兩個民族的CCR2b-64I和SDF1-3′A等位基因群體分布符合Hardy-Weinberg平衡，在性別之間分布無顯著差異国产免费黃色视频。

To inquire into association between susceptibility to AIDP, AMAN and frequencies of HLA alleles and possible differencies in distribution of HLA alleles betwen AIDP and AMAN by genomic typing for HLA-class Ⅰ, class Ⅱ alleles, and to try to found out the effects of self intrinsic fators of GBS patients on occurence of two subtype from immunogenetic angle.

通過對AIDP和AMAN兩種GBS亞型的HLA-Ⅰ類和Ⅱ類等位基因的分型欧美一级做一级A，探討兩種亞型的易感性與HLA等位基因分型的關(guān)系以及兩種亞型在HLA等位基因分布上可能存在的差異，從免疫遺傳學(xué)角度尋找自身內(nèi)在因素在GBS不同亞型發(fā)病中的可能作用。

The novel PCR technology can accurately categorize the spectrum of FMR1 alleles, including alleles previously considered too large to amplify; reproducibly detect low abundance full mutation alleles; and correctly infer homozygosity in female samples, thus greatly reducing the need for sample reflexing to Southern blotting.

這種新型的PCR技術(shù)可以準(zhǔn)確判斷FMR1基因的類型日韩最新无码资源站AV，包括傳統(tǒng)PCR不能擴(kuò)增的大片段羞羞漫画官方网站在线观看。該法還能檢測低濃度的全突變條帶，并且重復(fù)性好免费一看一毛片。同時該法還能準(zhǔn)確判斷女性樣本中的純合子极品欧美，因此大大減少了需要Southern雜交的樣本量。

To investigate the methods to effectively and simply assess the CAG repeat size of HD gene which was necessary for gene diagnosis of Huntington disease, the sequence including polymorphic CAG repeat of HD gene was amplified by PCR with TaKaRa LA Taq DNA polymerase and GC buffer. PCR products were analyzed on polyacrylamide gel to distinguish normal alleles from HD alleles. The DNA fragments of affected alleles were recovered from polyacrylamide gel as templets for secondary PCR. The secondary PCR products were cloned into T vector for sequencing analysis to determine CAG repeat size. A total of 20 normal individuals and 3 members from a HD pedigree were included in this study.

為了簡單高效檢測HD基因開放閱讀框5'端n三核苷酸重復(fù)序列动漫精品一级AV片在线观看，建立快速準(zhǔn)確的亨廷頓病(Huntington disease3p合辑欧美一区二区， HD)基因診斷方法2021韩国午夜理伦三级无码，應(yīng)用TaKaRa LA Taq DNA聚合酶配合GC buffer擴(kuò)增HD基因包含n重復(fù)序列的目的片段户外露出在线播放，非變性聚丙烯酰胺凝膠電泳檢測后回收n拷貝數(shù)異常增多的目的片段，再次PCR擴(kuò)增后將產(chǎn)物連接至T載體黄色网站在线视频免费观看大全，進(jìn)行DNA測序確定CAG的拷貝數(shù)欧美男女a视频。