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objective to isolate and purify the antimicrobial peptides with anti-toxoplasma gondii activity isolated from the haemlymph of musca domestica larvae.methods the antimicrobial peptides of musca domestica larvae were induced by infection and injury were isolated and purified by trituration,centrifugalization and column chromatography.then the antimicrobial peptides with anti-toxoplasma activity were sieved by mtt colorimetric method and haemacytometry.results it was found that two antimicrobial peptides had anti-toxoplasma activity through resource s cationic column chromatography and superdex g75 gel column chromatography.conclusion the two antimicrobial peptides with anti-toxoplasma activity existing in the haemlymph of musca domestica larvae had different anti-toxoplasma effect.

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Anti-MOG and anti-MBP antibodies predicted more frequent and earlier relapses. Of 39 seronegative patients, nine (23%) had a relapse, and time to relapse was 45 13.7 months. Of 22 patients with anti-MOG and anti-MBP, 21 (95%) relapsed, and mean time to relapse was 7.5 4.4 months. Of 42 patients with only anti-MOG, 35 (83%) relapsed within 14.6 9.6 months P .001 for both comparisons with antibody-seronegative patients.

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Anti-MOG and anti-MBP antibodies predicted more frequent and earlier relapses. Of 39 seronegative patients, nine (23%) had a relapse, and time to relapse was 45 13.7 months. Of 22 patients with anti-MOG and anti-MBP, 21 (95%) relapsed, and mean time to relapse was 7.5 4.4 months. Of 42 patients with only anti-MOG, 35 (83%) relapsed within 14.6 9.6 months P .001 for both comparisons with antibody-seronegative patients.

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Coumarins are a group of important natural compounds, and have been found to have multi-biological activities such as anti-HIV, anti-tumor, anti-hypertension, anti-arrhythmia, anti-osteoporosis, assuaging pain, preventing asthma and antisepsis.

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Mao not only the Chinese big bourgeoisie and the capitalist class is divided into two parts, the national bourgeoisie, but again the big bourgeoisie is divided into pro-Japanese and Anglo-American faction factions; not only that the national bourgeoisie have a revolution and the two sides to compromise, and that Britain and the United States to send the big bourgeoisie is also the two sides of the anti-Japanese and anti-communist, and anti-Japanese and anti-communist and each of its two sides; and based on the distinction between the two sides of the above understanding of Mao Zedong with the various parts of the development of the bourgeoisie and the struggle against a series of joint and differentiated policy so as to achieve, consolidate and develop the anti-Japanese national united front and the second KMT-CPC cooperation, for all the final victory of the Anti-Japanese War, laid a solid theoretical foundation and basis of a policy.

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