In 2000, F. LUCA proved that Fermat number are anti-sociable numbers, and in 2005, M. H. LE proved all powers of 2 are anti-sociable numbers. We have used the method of M. H. LE to obtain some new results of the anti-sociable numbers. For every integer n containing prime divisors that are 1 mod 4, let p mod 4 be an arbitrary prime divisor of n. There is at least one anti-sociable number in n^2, p^2n^2, p^4n^2, and p^6n^2. Therefore we can prove that anti-sociable numbers have positive density in perfect square numbers. We also give a method to find the exact anti-sociable numbers.

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objective to isolate and purify the antimicrobial peptides with anti-toxoplasma gondii activity isolated from the haemlymph of musca domestica larvae.methods the antimicrobial peptides of musca domestica larvae were induced by infection and injury were isolated and purified by trituration,centrifugalization and column chromatography.then the antimicrobial peptides with anti-toxoplasma activity were sieved by mtt colorimetric method and haemacytometry.results it was found that two antimicrobial peptides had anti-toxoplasma activity through resource s cationic column chromatography and superdex g75 gel column chromatography.conclusion the two antimicrobial peptides with anti-toxoplasma activity existing in the haemlymph of musca domestica larvae had different anti-toxoplasma effect.

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Anti-MOG and anti-MBP antibodies predicted more frequent and earlier relapses. Of 39 seronegative patients, nine (23%) had a relapse, and time to relapse was 45 13.7 months. Of 22 patients with anti-MOG and anti-MBP, 21 (95%) relapsed, and mean time to relapse was 7.5 4.4 months. Of 42 patients with only anti-MOG, 35 (83%) relapsed within 14.6 9.6 months P .001 for both comparisons with antibody-seronegative patients.

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