Exogenous E2 alone has no effect on cell viability and apoptosis of H9C2 cells, but it can decrease the sensitivity of H9C2 cells to H_2O_2,hence,protect cells against apoptosis caused by oxidative stress.2Exogenous E_2 has downregulation effect on TβRⅠand TβRⅡof H9c2 cells,blocking ER may delete this effect of estradiol.H9c2 cells express ERβonly,suggests that E_2 may exert modulating effect on TGF-βpathway through ERβ.

外源性E2本身并不能影響H9c2細(xì)胞凋亡黄色免费cnm，但能夠降低H9c2細(xì)胞對(duì)H_2O_2的敏感性亚洲图片第一页，保護(hù)細(xì)胞抵抗氧化應(yīng)激引起的凋亡性交网在线。2外源性E2對(duì)H9c2細(xì)胞的TβRⅠ以及TβRⅡ具有下調(diào)作用求AV在线网站，阻斷ER可消除E2對(duì)TβRⅠ和TβRⅡ的下調(diào)作用九九九在线精品视频；E2可進(jìn)一步通過TGF-β通路降低受體后磷酸化smad2/3的水平真人av在线免费看；H9c2細(xì)胞僅表達(dá)ERβ，提示E2可能是通過ERβ發(fā)揮其對(duì)TGF-β通路的調(diào)控作用国产馆在线观看。

At Er~(3+) doping concentration range 0.1-1.5 mol%, Er~(3+) first arrived at ~4F_(7/2) energy level by excited state absorption, then rapidly relaxed to ~2H_(11/2) and ~4S_(3/2) energy levels, the population of which increased, the remarkable upconversion green emission was obtained when Er~(3+) directly went back to ground state by radiative transition.

Er~(3+)濃度在0.1-1.5 mol％時(shí)妓女在线网，Er~(3+)通過激發(fā)態(tài)吸收躍遷到~4F_(7／2)能級(jí)，后迅速無輻射弛豫到~2H_(11／2)久草手机视频在线观看、~4S_(3／2)能級(jí)色、操国产，~2H_(11／2)和~4S_(3／2)能級(jí)上Er~(3+)的布居數(shù)增多，Er~(3+)直接輻射躍遷回基態(tài)黄色一级片一，上轉(zhuǎn)換發(fā)射以綠光為主欧美一级免费播放。

ERα is the major subtype of estrogen receptor in vaginal tissue of rats. ERα and ERβ expressions are down-regulated in the vaginal tissues after ovariectomy. Our findings show that estradiol valerate can up-regulate the expression of ERα but ERβ.

ERα是大鼠陰道優(yōu)勢(shì)表達(dá)的雌激素受體亞型；去勢(shì)后陰道ER亞型表達(dá)下調(diào)凹凸视频天堂不卡在线观看，以ERβ明顯女人高潮爱AA片一级视频；戊酸雌二醇可明顯上調(diào)去勢(shì)大鼠陰道ERα的表達(dá)，但不上調(diào)ERβ的表達(dá)色婷婷全国Av免费观看。

Nm23, VEGF and ER can be used as markers in the prognostication of breast cancer. Patients with nm23, ER positive and VEGF negative have better postoperative prognosis. Expression of ER can be used as an early marker, Postmenopausal breast cancer patient should apply more active endocrinotherapy.

我們認(rèn)為三男一女av，乳腺癌的發(fā)生與癌組織中的 nln23、pZI VEGF和 ER過度表達(dá)有密切相關(guān)黄页免费观看的视频在线观看，nln23陽性成年该看的免费视频、VEGF陰性和 ER 陽性的乳腺癌術(shù)后預(yù)后較好，癌組織中的m231000部国产怕怕怕精品、VE GF和ER表達(dá)可以作為判斷乳腺癌預(yù)后的指標(biāo)十八岁禁止黄片；ER的表達(dá)可以作為乳腺癌的早期標(biāo)記物；絕經(jīng)后乳腺癌病人應(yīng)采取更積極的內(nèi)分泌治療。

Results: 1 Intense ERα immunoreactivity localized in the hypertrophic and maturative layer, and some immunoreactivity was found in osteoblasts of mandible and temporal bone, while no immunoreactivity was found in the disc and synovium. 2 The expression of ERα in male rats TMJ cartilage was higher than that in female ones. 3 In the condyle cartilage of male rats, the density of ERα positive cells decreased with age, which kept stable after 16 weeks of age. 4 In the condyle cartilage of male rats, the density of ERα positive cells was stable from birth to 8 weeks, but decreased from 16 weeks to 12 months, while the density in 18-month group recovered to the level of 8 weeks. Conclusion: TMJ is one of target organs of estrogen, and ERα plays an important role in the effect of estrogen on TMJ.

結(jié)果：1TMJ中ERα主要在髁突軟骨的肥大層和過渡層表達(dá)在线视频亚洲日韩，下頜骨和顳骨的骨細(xì)胞也有少量表達(dá)午夜欧美福利视频，而關(guān)節(jié)盤、滑膜中幾乎無表達(dá)国产成年精品,免费视频大全；2雄性SD大鼠髁突軟骨中ERα的表達(dá)明顯強(qiáng)于同齡的雌性大鼠99在线视频播放；3在雄性大鼠TMJ髁突軟骨中陽性細(xì)胞密度隨年齡增長逐漸降低，16周以后逐漸維持在相對(duì)穩(wěn)定的水平日本最新免费二区三区；4雌性大鼠從出生后到8周齡陽性細(xì)胞密度基本穩(wěn)定亚洲欧美有码中文字幕，在16周齡至12月齡年齡組陽性細(xì)胞密度顯著降低，而在18月齡后又恢復(fù)到8周齡以前的水平欧洲A片视频在线观看。

All results above indicated that:The expression of ERβand p-ERβin mouse ovary at oestrous cycle and in early gestational period changed regularly, it showed that ERβand p-ERβhad important effects to ovaries development, ovarian follicles groth, oocyte maturation and form corepus luteum in female mouse ovary during oestrous cycle and in early gestational period.

以上結(jié)果表明：ERβ及其磷酸化形式——p-ERβ在小鼠發(fā)情周期以及妊娠早期卵巢中表達(dá)有規(guī)律性的變化午夜黄色网站免费成年人，揭示ERβ與p-ERβ在雌性小鼠發(fā)情周期及妊娠早期，對(duì)卵巢發(fā)育免费操逼漫画、卵泡生長色秀视频久久久、卵母細(xì)胞成熟和黃體形成有重要的作用。

The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P＜0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P＜0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝臟ERα及其mRNA基因的表達(dá)分布于肝細(xì)胞及肝臟非實(shí)質(zhì)細(xì)胞亚洲www日本，特別以肝臟中央靜脈和門脈周圍為主a片试看一区二区；卵巢切除減少ERα及其mRNA基因的表達(dá)（P＜0.05）；雌二醇治療在肝纖維化和卵巢切除大鼠均提高肝臟ER及其mRNA基因的表達(dá)（P＜0.05）刺激影院免费网站在线观看，其增加程度與肝臟組織學(xué)損傷欧美黄色免费观看网站、纖維化指標(biāo)的降低程度以及肝臟膠原沉積減少相平行。

Conclusions1男人的天堂国产精品、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2www自拍偷拍、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4福利影院大全、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

結(jié)論1欧美福利专区、E_2可增加Jurkat細(xì)胞的凋亡，并增加Fasa黄网站免费观看、FasL的蛋白表達(dá)人妻日韩综合诱惑色，且其作用與E_2的劑量和處理時(shí)間呈正相關(guān)。2欧美性爱精品一级片、Jurkat細(xì)胞上存在ERα人人操人人看人人搞、ERβ的表達(dá)真人版AV黄色网站，且E_2可上調(diào)這兩種受體的表達(dá)日韩丰满自拍视频在线，E_2劑量越大，ER表達(dá)量越高大黄色一级片。3欧美一区二区一级视频免费看、E_2可能通過ERβ發(fā)揮其促進(jìn)Jurkat細(xì)胞凋亡的作用。4、E_2能增加Jurkat細(xì)胞中NF-κB的轉(zhuǎn)錄活性欧美性一级a视频一级a视频，Jurkat細(xì)胞中NF-κB活性增加有促進(jìn)凋亡的作用插进去A片免费在线观看视频。

PL spectra indicate that the emission bands at 515 and 542 nm correspond to the 2H(subscript 11/2)→4I(subscript 15/2) and 4S(subscript 3/2)→4I(subscript 15/2) transitions of Er(superscript 3+), respectively. In the samples, the cerium dopant exists as Ce(superscript 3+) and Ce(superscript 4+). Ce(superscript 3+) sensitizes Er(superscript 3+) and enhances the luminescence intensity of the doped nanorods remarkably and energy transfer from Ce(superscript 3+)→Er(superscript 3+) was observed.

對(duì)發(fā)光機(jī)理的初步研究表明：發(fā)光分別對(duì)應(yīng)于Er(上標(biāo) 3+)的2H(下標(biāo) 11/2)→4I(下標(biāo) 15/2)，4S(下標(biāo) 3/2)→4I(下標(biāo) 15/2)躍遷国产精品电影久久久久电影院，鈰離子以Ce(上標(biāo) 3+)和Ce(上標(biāo) 4+)兩種形式存在于體系中18禁成年大片免费网站，Ce(上標(biāo) 3+)對(duì)Er(上標(biāo) 3+)起敏化作用，可以顯著增強(qiáng)β-BBO：Er(上標(biāo) 3+)/Ce(上標(biāo) 3+)/Ce(上標(biāo) 4+)納米棒的發(fā)光強(qiáng)度亚洲一区二区三区在线看，存在Ce(上標(biāo) 3+)→Er(上標(biāo) 3+)的能量傳遞過程中文字幕激情亚洲。

Er concentration.2. With the analysis of the optical parameters calculated by Judd-Ofelt theory and the lifetime of ~4I_(13/2) of Er gotten in experiment, we investigated Y dopings dispertion effect and influence to the environment of Er .3. In the research of Er/Yb/Al co-doped laser glass, we fixed the Er:Yb at 1:6 and varied the Al concentration.

我們利用Judd-Ofelt理論，計(jì)算得到了Er/Y共摻玻璃的Judd-Ofelt強(qiáng)度系數(shù)射,黄色视频、光譜質(zhì)量因子欧美二区乱伦视频、自發(fā)輻射弛豫率和能級(jí)壽命等光譜參數(shù)，并且給出了不同Y摻雜濃度下Er~(3 )離子的熒光量子效率大学生粉嫩12p国产；結(jié)合Er~(3 )離子~4I_(13/2)能級(jí)的熒光壽命制服丝袜人妻日韩在线，深入探討了摻Y(jié)對(duì)高濃度Er~(3 )離子在硼硅酸鹽玻璃中分布的彌散作用和對(duì)配位場(chǎng)環(huán)境的影響。