Objective: To investigate the protective effects and potential mechanism of genistein on prevention and treatment of transplant arteriosclerosis.

目的：研究染料木黃酮對移植動脈硬化的保護(hù)作用及初步探討其可能的作用機(jī)制。

Bergan cautioned that much is unknown about use of genistein in preventing cancer spread.

伯根告誡說一级毛片免费网站看，很多是未知的關(guān)于使用金雀異黃素在預(yù)防癌癥的蔓延。

Bergan and his team have previously demonstrated in prostate cancer cell cultures that genistein inhibits detachment of cancer cells from a primary prostate tumor and represses cell invasion.

伯根和他的團(tuán)隊先前已表明，在前列腺癌細(xì)胞文化支隊金雀異黃素抑制癌細(xì)胞從小學(xué)前列腺腫瘤和represses細(xì)胞的入侵亚洲欧洲性爱。

Results of some laboratory studies of genistein have also been mixed, but most have shown favorable results, Bergan said, demonstrating that genistein can inhibit a variety of cell molecules including tyrosine kinases, which activate proteins by attaching them to phosphate chemicals.

結(jié)果，一些實驗室的研究金雀異黃素也有好壞參半国产精品久久久久精品三级一区，但大多數(shù)表現(xiàn)出良好的結(jié)果在线看一级片视频软件，伯根說，這表明金雀異黃素能抑制多種細(xì)胞的分子www熟女，包括酪氨酸激酶丝袜美女人人摸人人操，激活蛋白質(zhì)將它們附加磷酸鹽的化學(xué)品免费观看黃色A片一级视频快进。

AIM: To improve the in vivo activity of genistein by increasing the solubility and permeability of genistein.

目的：通過提高染料木素的溶解度和滲透速率來改善染料木素的小腸吸收及體內(nèi)活性。

Results Expressions of PCNA in HPFs was 0.335±0.017, 0.327±0.006, 0.314±0.043, 0.306±0.030 and 0.303±0.019 respectively at the concentration of 3.125, 6.25, 12.5, 25, 50 μg/ml of genistein and control group was 0.383±0.030, exhibiting genistein inhibited the growth of HPFs at a concentration-dependent manner.

結(jié)果 當(dāng)染料木黃酮的質(zhì)量濃度≥3.125 μg/ml時能有效地抑制細(xì)胞表達(dá)增殖細(xì)胞核抗原免费观看黄色视频。

RESULTS: The morphology of RGC was changed by genistein treatment. The number of cell protuberance and suspended cells raised as genistein concentration increased.

結(jié)果：染料木黃酮改變了RGC的形態(tài)人人干操操操插，隨著濃度的升高，突起和漂浮細(xì)胞的數(shù)量增加偷拍偷窥网。

The aforesaid experimental results suggested that genistein could enhance the antioxidant ability of body ,ameliorate the functions of hematogenic system, strengthen the immune system, raise survival rate of irradiated mice without obviously side effect. So we can conclude that genistein has anti-radiation property and may be a good radioprotective functional food factor.

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These compounds were identified as follows:chrysophanol (FP-1),physcion(FP-2),eriosematin(FP-3),scoparone(FP-4),lupeol(FP-5),betulinic acid(FP-6),3\',4\'-Dihydroxy-trans-cinamic acid octacosyl ester(FP-7),β-sitosterol (FP-8),flemiphilippinone A(FP-9),monopalmitin(FP-10),emodin(FP-11),islandicin (FP-12),salicylic acid(FP-13),p-methoxyphenylpropionic acid(FP-14),trideca-1, 3-diene(FP-15),lupinifolin(FP-16),flemichin D(FP-17),flemiphilippinin A(FP-18), auriculasin(FP-19),erythrinin B(FP-20),6-C-prenylluteolin(FP-21), 8-(1,1-dimethylallyl) genistein(FP-22),flemiphilippinin E(FP-23),flemiphilippinin F (FP-24),5,7,3\',4\'-tetrahydroxy-6,8-diprenylisoflavone(FP-25),flemiphilippinin D (FP-26),dorsmaninsⅠ(FP-27),osajin(FP-28),6,8-diprenyleriodictyol(FP-29), lupinalbin A(FP-30),genistein(FP-31),3\'-O-methylorobol(FP-32),orobol(FP-33), 5,7,2\',3\',4\'-pentahrdroxyflavone(FP-34),the mixture of biochanin A and prunetin (FP-35 and 36),genistin(FP-37),sophororicoside(FP-38),3\'-O-methylorobol-7-glucoside(FP-39),the mixture of sissotrin and prunetin 4\'-O-β-D-glucoside(FP-40 and 41),adenosine(FP-42) and luteoloside(FP-43,mixture).

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MTT assay FAK signaling pathway inhibitor genistein on human corneal epithelial cell cytotoxicity;RT-PCR detection of human corneal epithelial cells adhesion to fungus at different times,extracellular matrix protein including laminin,fibronectin,FN glass,Ⅳcollagen,transmembrane protein integrinαⅤ,integrinβ1(ITGβ1),as well as the FAK signaling pathway FAK1,FAK2 and Paxillin gene expression;Western blot detection of the signal transduction pathway adhesion-associated protein ITGβ1,FAK and PAX expression and the inhibition of genistein. Immunocytochemical method was used to observe the LN,FN and FAK expression in human corneal epithelial cells during interaction with the fungues;Laser scanning confocal microscope had a cell positioning on FN,FAK and PAX,observed the changing of the human corneal epithelial cytoskeleton after stimulated by fungues;Quantitatived by flow cytometry to detect of human corneal epithelial cells with PAX at ITGβ1 fungal expression after adhesion;Optical microscopy quantitied the fungues and human corneal epithelial cell adhesion and recorded to determination the integral optical density afrer adhesion;Scanning and transmitted electron microscope observed the changing of cell ultrastructure after fungues and human corneal epithelial cell adhesion.

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