Methods: Separated 120 cases with glomerular diseases into chronic glomerular nephritis group (70 cases, including 33 cases with normal serum creatinine, 17 cases with azotemia, 20 cases with uremia, 33 cases accompanied with hypertension), acute nephritis group (12 cases), nephritic syndrome group (38 cases), and selected 30 healthy cases as control group. Detected concentration of NO in serum with nitrate reductase method, and made comparison among groups.

120例腎小球疾病患者分為慢性腎小球腎炎組（70例免费精品自在拍精选在线观看AV，其中血清肌酐正常33例色哟哟免费小黄片，氮質(zhì)血癥17例尺度视频在线黄页，尿毒癥20例伊人无码视频综合网，伴有高血壓33例）影音先锋最新av资源、急性腎炎組（12例）欧美天天、腎病綜合征組（38例），同期選擇30例健康體檢者作為對(duì)照組在线欧美h，采用稍酸還原酶法測(cè)定腎小球疾病患者及對(duì)照組血漿NO濃度中文字幕强奸乱伦国产，并對(duì)各組NO濃度進(jìn)行比較。

Methods Changes relating to glomerular function, structure and glomerular basement membrane ultrastructure were observed.

觀察低分子肝素對(duì)腎小球功能国产色色一级免费视频、形態(tài)及腎小球基底膜超微結(jié)構(gòu)的影響色热av。

The method of using it to distinguish glomerular and non-glomerular hematuria is easy and correct.

形態(tài)特異的G紅細(xì)胞鑒別腎小球性血尿，方法簡(jiǎn)單一级欧美片网站，結(jié)果正確三级视频在线免费观看。

Objective: To explore the differentiating method of glomerular hematuria from non-glomerular hematuria.

目的：探討用于鑒別腎小球性與非腎小球性血尿的檢驗(yàn)方法。

In addition, glomerular enlargement, hypertrophy, and glomerular mesangial deposits lead to a progressive glomerulosclerosis and eventual nephron loss.

因此七七久久，腎絲球體的擴(kuò)大美女黄色网站mmm，肥大，和腎絲球間質(zhì)沈積老熟妇仓乱视频一区二区，導(dǎo)致累進(jìn)式腎絲球體硬化欧美三级片黄色视频，以及最后一個(gè)腎臟小過(guò)濾器喪失。

Results Non-specific antibody increased distinguishingly in each groups after drug treatment 30 days, but all tested indexes showed no anychange in 2mg/ group. Glomerular basement membrane became thick in 10mg/ group after drug treatment 90 days, but it showed normal when treatment time was shorten to 30 days. The thickness of glomerular basement membrane was very serious in in 50mg/ group and liquid containing protein was found increasing in glomerular and tubular. The thickness of glomerular basement membrane didn't ameliorate after stopping drug 30 days.

結(jié)果 給藥后30天各給藥組動(dòng)物血清非特異性抗體明顯升高国外A片无码毛片免费视频。rhIL-1Ra 2mg/組其他檢測(cè)指標(biāo)均未見(jiàn)明顯地改變国产日韩制服丝袜第一页。rhIL-1Ra 10mg/組給藥后90天腎小球毛細(xì)血管基底膜明顯增厚，但此劑量給藥時(shí)間為30天時(shí)未見(jiàn)任何異常免费人城网站在线观看。rhIL-1Ra 50mg/組腎小球及腎小管中蛋白性液體量多欧美激情偷乱人伦小说视，小球毛細(xì)血管基底膜增厚更為嚴(yán)重，且停藥30天后基底膜增厚程度仍未見(jiàn)明顯減輕或改善露出在线。

Cases healthy subjects served as control. In addition, density of glomerular matrix membrane and quantity of cell in glomeruli were measured with CMIAS image analysis system by computer. Global sclerosis, cellular crescents, fiber or fibrocellular crescents were measured with Memphis scope. Tubulointerstitial lesions were examined with semi-quantitative grades (including O-III grades).Results Compared to normal control, there was a significant increase of urinary TGF-betaK IL-6 and Col-lV levels in patients with IgAN (p. 01). There were also significantly positive correlation between the levels of urinary TGF-betaK Col-IV and density of glomerular matrix membrane ., interstitial fibrosisp.

采用酶聯(lián)免疫吸附法測(cè)定尿TGF-β1(Transforming growth factor-β1)三级色频、尿IL-6(interleukin-6)和尿Col-Ⅳ(type Ⅳ Collagen)；采用免疫組織化學(xué)法檢測(cè)腎組織TGF-β1欧美A∨在线精品、Col-Ⅳ表達(dá)操操操操干干干干干；應(yīng)用CMIAS多功能真彩色病理圖像分析系統(tǒng)對(duì)腎小球基質(zhì)基底膜面密度和細(xì)胞個(gè)數(shù)進(jìn)行半定量測(cè)定97人妻人人操人人摸；對(duì)球性硬化、節(jié)段硬化亚洲Va欧美va国产综合久久、細(xì)胞新月體及纖維或纖維細(xì)胞新月體所占腎小球百分?jǐn)?shù)和腎小球IgA沉積免疫熒光強(qiáng)弱的判斷采用Memphis法進(jìn)行評(píng)分一级黄色日逼视频看看；腎小管間質(zhì)病變程度采用光鏡下半定量分級(jí)法(包括0-Ⅲ級(jí))。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

結(jié)果 ①IgAN患者尿TGF-β1亚洲欧美丝袜精品、IL-6少妇高潮太爽了在线观看、Col-Ⅳ水平較健康人明顯增高(P＜0.01)，該變化與血中的濃度無(wú)關(guān)(P＞0.05)在线观看中文字幕在线；②尿TGF-β1水平與小管間質(zhì)TGF-β1陽(yáng)性表達(dá)呈正相關(guān)(P=0.000)毛片基地久久伊人91x32.cc，而與小球TGF-β1陽(yáng)性表達(dá)無(wú)關(guān)(P＞0.05)，尿Col-Ⅳ水平與小球和小管間質(zhì)Col-Ⅳ陽(yáng)性表達(dá)均呈良好的相關(guān)性(P＜0.01)97精品视频在线观看免费专区，還與小管間質(zhì)TGF-β1陽(yáng)性表達(dá)呈正相關(guān)(P＜0.05)：③小球Col-Ⅳ陽(yáng)性表達(dá)與腎組織慢性病變密切相關(guān)(P＜0.05)自拍国语日韩欧美视频在线播放，小管間質(zhì)Col-Ⅳ和TGF-β1陽(yáng)性表達(dá)均與腎小管間質(zhì)病變呈良好的相關(guān)性(P＜0.01)，而小球TGF-β1陽(yáng)性表達(dá)與腎組織損傷無(wú)關(guān)(P＞0.05)午夜福利A片1000无码免费；④尿TGF-β1人人操、人人射、人人爱、Col-Ⅳ水平與腎小球基質(zhì)基底膜面密度、小管間質(zhì)病變呈正相關(guān)(P＜0.01)亚州A√，與小球內(nèi)細(xì)胞數(shù)呈負(fù)相關(guān)(P＜0.05)在线观看a的网站，該結(jié)果與其在組織中的表達(dá)一致；尿IL-6水平浙江大學(xué)碩士學(xué)位論文尿TGF一B一一级WWW、IL一6和Col一IV在IgA腎病中的應(yīng)用價(jià)值與基質(zhì)基底膜面密度三级爆乳黄片在线看、球性硬化、纖維或細(xì)胞纖維新月體所占腎小球百分?jǐn)?shù)及小管間質(zhì)病變均有顯著的相關(guān)性(F.05)国产黄片,A片；在輕度腎病理?yè)p傷時(shí)www.干干色，尿'l'G卜pl、I卜6欧美性爱三级网站、Col一IV水平即升高日本操毛小a片，而尿Col一W在反映細(xì)胞外基質(zhì)積聚和間質(zhì)纖維化程度上比尿TGF一pl和IL一6有更好的相關(guān)性。

Results The according perception of Normocytic, Microcytic and Non-classified RBC between phase contrast microscope and UF-100 urine sediment analytic instrument RBC-info are 91.4%, 94.4%, 83.3% respectively, the according perception between phase contrast microscope and RBC-P70Fsc are 94.9%, 95.7%, 94.7% respectively, and the according perception between phase contrast microscope and RBC Fsc-DW are 84.4%, 86.8%, 90.5% respectively, the specificity of UF-100 and phase contrast microscope in glomerular hematuria and non-glomerular hematuria are 84.3%, 88.1% and 83.3%, 87.9% respectively.

結(jié)果 觀察相差顯微鏡與流式細(xì)胞分析儀RBC-info尿紅細(xì)胞均一型www.天堂AV网站、變異型狂插美女阴道动态、混合型形態(tài)符合率分別為91.4%、94.4%国产一级AA片在线视频、83.3%国产在线91免费，與RBC-70Fsc符合率分別是94.9%、95.7%美女下部隐私扒开视频无遮挡、94.7%久草视频在线一区二区三区，與RBC-Fsc-DW符合率分別是84.4%88888视频搞基、86.8%玖玖色在线免费视频、90.5%8x8ⅹcom永久免费视频，流式細(xì)胞分析儀與相差顯微鏡的特異性在腎小球性血尿和非腎小球性血尿分別是84.3%、88.1%和83.3%色色综合电影网站、87.9%久久婷婷国产麻豆91天堂。

The expressions of VEGF mRNA in renal cortex in B and group C increased greatly compared with A group at 8th week(P.01), And the expression was decreased more in C group than that in B group at the 8th week;④The light microscopes results showed that no pathological changes in group A; pathological changes were much obvious in group B:glomerular capillary lumen tumbling,lumens blocked,mesangial region widened,basal lamina thicking,mesenterium base inceased,the volume of glomerulus become large,cell population increased,renal tubule vacuolization, renal interstitium was infiltrated by lots of lymphocyte and mononuclear macrophage; pathological changes in group C was light,only see glomerular capillary lumen lightly stegnosis,few lymphocyte infiltrating.

免疫組化結(jié)果顯示第8周B組大鼠腎皮質(zhì)VEGF蛋白含量較A組顯著增加(P.01)，C組VEGF含量較B組有明顯減少(P.01)国产精品黄片在线播放，C組較A組表達(dá)量仍然增加(P.01)亚洲福利日韩看片无码；③第8周B組腎皮質(zhì)VEGF mRNA表達(dá)較A組有明顯上調(diào)(P.01)，與B組相比久操手机在线网站播放，辛伐他汀可以明顯減少C組腎皮質(zhì)VEGF mRNA表達(dá)一级做a爱全免费视频在线；④光學(xué)顯微鏡下A組腎小球毛細(xì)血管腔均勻一致，無(wú)狹窄亚洲a毛网站，腎小管-間質(zhì)無(wú)炎癥細(xì)胞浸潤(rùn)91在线精品国自产拍。B組則病變較明顯：大鼠腎小球毛細(xì)血管袢塌陷，管腔閉塞黄色精品视频在线观看，系膜區(qū)增寬精品黄黄久久久免费看，基膜增厚和系膜基質(zhì)增多，腎小球體積增大成人播放日韩在线播放AV，出現(xiàn)玻璃樣變免费看黄色短片；腎小管尤其是近區(qū)小管腫脹、變性淫荡视频网页、空泡形成亚洲熟女偷窥综合网，腎間質(zhì)可見(jiàn)大量淋巴細(xì)胞和單核巨噬細(xì)胞浸潤(rùn)。C組病變較輕A级黄片在线视频免费，可見(jiàn)腎小球毛細(xì)血管管腔輕度狹窄欧美在线视频播放，腎小管-間質(zhì)見(jiàn)少量淋巴細(xì)胞浸潤(rùn)。