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In particular, it is unknown how the relevant neural substrates function as a network to mediate perspective-taking during the task requiring understanding other's belief. The current work first developed a new psychological paradigm that excludes potential confounds such as the processing of language, biological motion, episodic memory and causal coherence in the paradigms used in previous studies. I recorded neural activities associated with mental inference task using functional magnetic resonance imaging and electroencephalography in order to investigate the functional roles of several brain areas (i.e. precuneus, MPFC, etc.) that engage in understanding other's belief. I also proposed a computational model based on the neuroimaging results that simulated the neurocognitive mechanism underlying cortical dynamics in correct judgment of other's belief.

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The model of brain concussion of rat can be established successfully using iron pendulum hitting device; 2. The spatial learning and memory deficits of the rats are detected by MWM in early period post-BC(from 1 to 3 days after BC); 3. Pycnosis degeneration or necrosis neurons of the cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation are identified in BC rats; 4. There are significantly changes in the number and activity of cholinergic neurons in the basal forebrain and brainstem reticular formation after BC; 5. The change of cerebral neurons and cholinergic neurons correlate with cognitive deficits in BC rats .

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After 5 days we began to measure the abilities of learning and memory in the Morris water maze. The avoiding latency, the frequency of passing the platform and the stay time in the aim quadrant were determine in mice. The activities of TchE and MAO in the cerebra of mice were detected.

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