The various parameters observed were the following : modification of the skin status, coat, eyes, mucous membrane, apparition of secretions or excretions and neurovegetative reaction (tears, piloerection, variation of the pupillary diameter, variation of the respiratory rhythm…), walking modifications, changes in the posture, reaction to manipulation, presence of clonic or tonic movements, stereotyped or unusual behaviors, sensorial reactivity to various stimuli (auditory, visual, proprioceptive), prehension strength and moving activity.

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Appetite , expression , hair color ,etc.: Compared with the group of normal rats, from the 2nd week when making the mould, the rats' appetite of each modle group has been reducing in various degree ,the eyes does not sparking any more, the weight dropping , piloerection , epilate , and the fur is owed the gloss , hunchbacked , languid , slow in reaction, the activity reduces, it is apt to irritabling etc. aggravate continuously.

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Practically, the fecal granules of rats are easily to be scored and the existence of urinal incontinence, piloerection and tremble are easily determined.

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Test results: Administered on Day 14 after first injection, the animals in the first group (No. 1, 2, 3) did not present any reactions such as piloerection, jitter, cough, scrunching, dyspnea conulsion or death.

實(shí)驗(yàn)結(jié)果：第一次注射后14天由股靜脈給藥的第一組動(dòng)物（1欧美午夜视频免费，2国内精品偷拍小视频，3號(hào)）藥后未見動(dòng)物有豎毛，顫抖99免费在线视频，咳嗽欧美日韩在线95页，蜷縮，躁動(dòng)大鸡八网站，呼吸困難99视频10精品视频在线，抽搐以至死亡現(xiàn)象出現(xiàn)。

Administered on Day 14 after first injection, the animals in the second group (No. 4, 5, 6) did not present any reactions such as piloerection, jitter, cough, scrunching, dyspnea conulsion or death either.

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Results compared with the control group, the rats in the lactacystin group began gradually to have some behavioral symptoms, for example, the spontaneous motors decreased progressively, tardive dyskinesia, piloerection, tremor, contralateral rotations induced by apomorphine increased gradually.

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Meanwhile, we discussed the founded background of ZIDIANKELI, and we treated the ITP according to the idea"the origin of the disease is the Qi-Deficiency, Blood Stasis run through the course of the disease" and make the principle of the treatmentstrengthening Qi and tonifying the deficiency, removing the blood stasis and producing the fresh blood. 3. Result 3. 1 Experimental Research 3. 1. 1 The effects of ITP model mice's general state and swimming time by the treatment of ZIDIANKELI After the fifth day of establishing the model, the model group appeared following symptoms: activity reduced, liking to gather together, piloerection, no sheen of the hair, swimming time reduction. To compare with the normal group, it is has statistical significance.

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Behavior: Rage, attack reaction or fighting associated with hissing, growling, spitting, piloerection, pupil dilation, biting.

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