A good wine or a sunripe wild strawberry activates a whole array of odorant receptors, helping us to perceive the different odorant molecules.

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In the fruit fly Drosophila, not all olfactory sensory neurons express a seven transmembrane odorant receptor, suggesting that other types of odorant receptors might exist.

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This is a really mimicking bioelectronic nose technology, which can detect odors by using chips such as microelectrode array to record action potential representing the banding of odorants and odorant receptors in cell membrane.

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When cell receptors activated by OEA were blocked, memory retention effects decreased.

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The opioid receptors mainly distribute at prefrontal lobe(obitofrontal gyrus, medial superior frontal gyrus, superior frontal gyrus), paralimbic cortices (cingulated cortex and hippocampus), insular cortex、pallidum and the opercular section of frontal lobe and parietal lobe. These results corresponded with the classic theories on PET neurorecepotors imaging.

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These kinases play an important role in the signal transduction of opioid receptors, tolerance and dependence of opiate.

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As the main influence of weightlessness in space focused on the otolith receptors.The test of otolith function is of great importance.

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Because nicotine is so similar to acetylcholine, and binds to cholinergic receptors, nicotine in excess produces the same overstimulation and toxicity.

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Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

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However, a growing number of studies suggest that excessive extracellular glutamate and resultant overstimulation of its receptors cause excitotoxic roles and lead to neuronal damage in several pathological conditions such as cerebral ischemia. Normally, the excitatory postsynaptic roles of glutamate are terminated by the activities of high-affinity sodium dependent glutamate transporters that locate on neuroglial cells and neurons near the synaptic cleft, which are thought to play important roles in inactivating released glutamate and keep it below toxic levels in the extracellular space.

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