We discovered that the mechanisms of borneol opening BBB involved (1) promoting the tight junction of endothelial cells opening:(2) increasing the quantity of pinocytosis vesicle in endothelial cells and enhance the pinocytosis;(3) inhibiting the activation of P-glycoprotein (P-glycoprotein is an efflux pump of drugs) and increase the permeability of BBB;(4) reducing the expression of intercellular adhesion molecule-1 in brain microvessel endothelial cells;(5) increasing the concentration of Ca〓 in brain microvessel endothelial cells;(6) increasing the activation of eNOS in brain microvessel endothelial cells.

隨后尤物网视频在线，在對冰片開放血腦屏障的機制作進一步的研究時又發(fā)現(xiàn)美女网页黄a，冰片開放血腦屏障的機制包括以下幾個方面：(1)冰片可使血腦屏障內(nèi)皮細胞間的緊密連接開放；(2)冰片能使內(nèi)皮細胞內(nèi)的囊泡數(shù)量增加欧美一级A片视频在线，吞飲功能增強国产精品视频熟女一区二区；(3)冰片能抑制P-糖蛋白的活性（P-糖蛋白是一種藥物外排泵），而使血腦屏障的通透性增加国产又大又粗又爽又黄网站；(4)冰片能使腦微血管內(nèi)皮細胞ICAM-1表達量減少中日韩精品高清在线视频观看网站；(5)冰片使腦微血管內(nèi)皮細胞內(nèi)的Ca〓濃度升高；(6)冰片可升高腦微血管內(nèi)皮細胞eNOS的活性97人人爽日日动。

Pregnancy toxaemia ofass and mare 8 Characterized by an overabundance of blood9 A treatment in which evacuated glass cups are applied to intact or scarified skin in order to draw blood toward or through the surface .

杯吸法欧美色欲综合一区二区，拔罐法一種醫(yī)療方法，把抽空的玻璃杯放在完好無損或劃破的皮膚上使血向體表聚集或放血出來贵在真实国产熟女露脸。

A treatment in which evacuated glass cups are applied to intact or scarified skin in order to draw blood toward or through the surface.

杯吸法欧洲一级毛片，拔罐法一種醫(yī)療方法，把抽空的玻璃杯放在完好無損或劃破的皮膚上使血向體表聚集或放血出來免费一极a片。

A treatment in which evacuate d glass cups are applied to intact or scarified skin in order to draw blood toward or through the surface.

杯吸法曰本另类女同专区久久精品，拔罐法一種醫(yī)療方法，把抽空的玻璃杯放在完好無損或劃破的皮膚上使血向體表聚集或放血出來美国一级做a一级视频。