A human promyelocytic leukemia cell mutant (HL-60-AR) with deficiency in HGPRT and resistance to 8-AG was established by treat〓nt of the HL-60 cells with MNNG and prescreened in 0.3% agar RPMI-1640 semisolid medium containing 8-AG. The mutant cells show the following characteristics:(1) resistant to cytotoxic action of 8-AG and growing vigorously in medium containing 20ug/ml 8-AG;(2) capable of forming 〓〓 colonies in soft agar medium in the presenee of 8-AG:(3) highly sensitive to HAT selective medium and fail to growing in HAT medium of form colonies in soft agar medium containing HAT;(4) completely deficinet in HGPRT activity; and (5) no radioactive silver grains over the mutant cells due to the absence of -hypoxanthine incorporation showed by radioautography.

一a一级爰做片免费观看、用MNNG誘變和8-AG進行抗性篩選，成功地建立了一株抗高濃度8-AG和完全缺失HGPRT活性的人早幼粒白血病細胞突變株(HL-60-AR)日韩A片综合视频，該細胞能抵抗8-AG的毒性作用91精品国产色综合久久不卡美美，對HAT選擇培養(yǎng)基十分敏感，檢測不到HGHRT活性黄色免费网站在线看，不能參入〓H一次黃嘌呤伊人久久久久一级毛片。

The results have shown that the SSS method for radiotherapy treated mouse models of lewis lung cancer with both spleen Qi and Yin deficiency, can markedly increase percentage of inhibiting tumuor, limit radiogenic damage to bonemarrow and perapheral blood, prevent immune organs from injuvry by radiotheray, improve immune funotion, enhance the activity of NK cells and IL-2, prompte formation of antibodies, having a good action of synergism and detoxification to radiotherapy on lung cancer.

研究結(jié)果表明激情图片亚洲乱伦，益脾養(yǎng)陰法能顯著增強Lewis肺癌脾氣陰兩虛證荷瘤受照小鼠的抑瘤作用，抑制放療對骨髓造血功能的毒性作用国产精品特黄特粗又长视频，保護外周血象国产精品尤物视频，并能拮抗放療對免疫器官的損傷作用，改善和促進荷瘤受照小鼠的免疫機能日韩A级毛片免费视频播放，增強NK細胞及IL-Ⅱ活性91在线免费精品，提高抗體產(chǎn)生能力，對肺癌放療具有較強的增效減毒作用2021色色。

Objective: To reduce the toxicity of ricin and reserve its antitumor activity.

目的：為了降低蓖麻毒素的毒性国产第一页精品12页，保留其抗腫瘤活性。

The in vitro anticancer activities of the ruthenium complexes were screened by MTT assay.

采用MTT法評價了3種異構(gòu)體對多種腫瘤細胞株的體外抗腫瘤活性以及對正常細胞的毒性日日射夜夜操。

Results showed LC_(50) of divalent mercury to swordtail fish were 0.84, 1.35, 1.71mg/L in 24h, 48h and 96h respectively, while LC_(50) of tetravalent selenium to swordtail fish were 6.64, 12.59, 17.91mg/L respectively.

結(jié)果表明：Hg+2對劍尾魚的 24www.操com、48、96 h的 LC50分別為 1.71快射视频在线播放网站、1.35黄色AV免费的网站、0.84mg/L；Se+4對劍尾魚24深夜福利在线视频、48日韩大陆一区二区三区在线观看、96 h的Lc50分別為17.91、12.59黄色片mmm,com、6.64 mg/L十八禁网址污；在濃度和毒性比都為1∶1的條件下，24 h都表現(xiàn)聯(lián)合作用久久精品店这里有精品，而48 hA片欧美在线播放免费网站、96 h則為拮抗作用。

The antioxidant MT exhibited an excellent antagonism to the teratogenesis induced by DPH.

MT對DPH誘發(fā)的動物發(fā)育毒性具有明顯的拮抗作用2020久久久久99精品。

Traditional Cancer chemotherapy is often hampered by an insufficient therapeutic index , lacking of specificity, and the emergence of drug — resistant cell subpopu-lations.

傳統(tǒng)的抗腫瘤藥物選擇性不高一级色逼影视，既殺傷腫瘤細胞，也損害體內(nèi)繁殖旺盛的細胞或某些特定類型的正常細胞在线播放一级AAA，常出現(xiàn)較明顯的毒性反應(yīng)538国产精品一区二区免费视频。

The joint toxicity was evaluated by different methods, including toxicity unit,additive index, similarity parameter and mixtures toxicity index. The results show that the binary joint effects of phenol and toluol mixed with SDS are synergistic, while the binary joint effect of SDS and nitrobenzene is antagonistic. The environment risk of some compounds will be enhanced because of the joint of SDS.

研究結(jié)果表明： 4種不同的評價方法對SDS與取代芳烴苯酚、甲苯和硝基苯的聯(lián)合效應(yīng)評價結(jié)果具有較好的一致性欧美理论片92理论午夜片，即SDS與苯酚免费黄色网站啊啊啊、甲苯的二元混合體系的毒性表現(xiàn)為不同程度的協(xié)同作用，而與硝基苯則表現(xiàn)為弱拮抗作用欧美另类69XXXXX义；對環(huán)境存在風(fēng)險性的陰離子表面活性劑SDSjizz在线，當(dāng)與一些有毒有害物質(zhì)共存時會增加該類物質(zhì)的環(huán)境風(fēng)險性。

Oxidative damage of multi-organ tissues, accumulation of metabolites and change of anti-oxidation in host may be main cause that induce formation of toxemia and oxidative damage of central nervous system of mice with trichinosis.

宿主多個臟器組織的氧化損害、氧化代謝毒性產(chǎn)物在機體內(nèi)的蓄積以及抗氧化能力的改變等因素可能是造成宿主毒血癥的形成以及中樞神經(jīng)系統(tǒng)損害的主要原因三级经典在线视频网站。

It has good antitumor activity , but is toxic to urinary system.

這類藥物的抗腫瘤活性好真实破苞痛痛痛视频，但是毒性也高。