Mercaptopurine ;; Mice ;; Drug Toxicity ;; Antineoplastic Agents ;; Microbiology ;; Injections, Intraperitoneal ;; Fermentation ;; Spleen

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It has been shown that boranophosphates are more lipophilic and nuclease-resistant than the normal phosphate diesters.

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San-Huang, so called Mesima in Japan and Korea, has been considered to be a traditional Chinese and Japanese medicine that was reported to be used as a stypti, both internally and externally, for treating uterine bleeding, and for blood in the urine. The modern researches proved that it is also an effective emmenogogue for amenorrhea and for treating leukorrhea. Extracts from hot water have been experimented to have antitumor and inhibit Sacroma 180 cancer cell abilities. The powdered fruiting body is taken in liquid or in pill form, and preparations can also be applied externally for pains in the abdominal region.

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Objective: To observe production of antibody to rhbFGF, its neutralizing activity and deposition in kidney in conducting toxicity study on repeated doses of recombinant human basic fibroblast growth factor in normal rhesus monkeys and Wistar rats.

目的：在獼猴和大鼠中進(jìn)行重組人堿性成纖維細(xì)胞生長因子的重復(fù)給藥毒性試驗(yàn)時(shí)亚洲各国三级片网站，觀察給藥后抗 rhbFGF 抗體的產(chǎn)生和抗體的中和性A片一A片一A片一a片，以及抗體在腎臟的沉積。