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This may eventually cause problems with patient access to these new therapies, the editorial suggests. All of the targeted therapies available to date are added onto conventional treatment, thus adding costs to the healthcare system."When the goal is to improve the chance for a cure, these new treatments seem to be well worth the expenditure," comments editorialist Hyman Muss, MD, from the Vermont Cancer Center, in Burlington."However, when the goal is to improve the quality of life or delay the time to progression by several months, as it is with many treatments for metastatic breast cancer, it is less clear whether the health system can and should bear these expenses."

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The limited merit of the Third Worldist perspective was that it directly countered the 'First Worldist' or Eurocentric view that innovation and change have always originated, and can only originate, in Euro-America.

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Aiming at the old ideas and behavior of primary and secondary schools teachers, the new curricula demand them acting some new roles in the curriculum implementation, and changing their roles from knowledge-transferee to learner, from dominator in classes to helper and guider of students" development, from passive curriculum player to positive curriculum constructor, from experientialist to researcher and from single person to others" cooperator.

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For two examples, result testifies that it is feasible to use in nonlinear restriction optimization. Chapter 3 is important part in the paper. Analyze and research BP network, concealed node number of network former frame newly. Give new supplement and advice about How to select study velocity and activation function in BP algorithm.

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