Alpha particle s have two positive charges and a mass of four atomic mass units; they are identical to helium nuclei.

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G/ml. After wt-p53 transfection and VCR treatment, the number of Bel-7402 cells was decreased; the cells were swollen severely with irregular projections; pyknosis, karyorrhexis and karyolysis were observed. After wt-p53 transfection, the expression of mdr1 and P-gp in Bel-7402 cells was down-regulated remarkably, and the expression of TopoⅡα was up-regulated.

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Brainstem is a middle station in messager transfer ring and take part in almost all the important function in central never system.

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However, since Barrington's nucleus contained not only projection neurons to the lumbosacral spinal cord, but also those to the nucleus of the solitary tract and thalamus, and dendrites of neurons located in its surrounding nuclei extend into the nucleus.

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Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

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Results In the condition of obturation and humidity, Neisseria gonorrhoeae in the leucorrheas survived longer in middle quantity than in few and mass. The survival time of Neisseria gonorrhoeae was short in dryness. In a few quantity (10/ml), karyote could phagocytize Neisseria gonorrhoeae and shorten its survival time, but in the quantity above 300/ml, karyote could prolong its survival time.

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Dinoflagellate have many traits different from prokaryotes and eukaryotes:the cells have nuclei, but the nuclear membrane is discontinuous; There are many chromosomes in the nuclei, but the chromosomes remain permanently condensed during cell cycle; The cristae of mitocondria is tubular, and the cells have no typical endoplasmic reticulum.

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Biochemical indicator such as TG and SF were unregulated while 1 system or 2 system reduced in peripheral blood; Bone marrow hyperplasia showed active or active obviously. Complete morphological nucleated cells mature erythrocytes or platelet hemophagocytic cells were found in 100% marrow slides. Marrow hemophagocytic cells were quantified as 0.5 to 11 per micro liter Median 4.2 per micro liter. Phagocytes showed smaller size single nucleus on one side. Submitting as rings cell plasm showed gray or salmon pink and cell showed disorder fringes.

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In general, this malaria parasites in the mature or nearly mature erythrocytes, schizonts usually large, occurre in mature erythrocytes with more 20 merozoites most commonly arranged in mass.

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The major clinical manifestation was lymph node enlargement found in all patients. Skin involvement and osteolysis were not frequent. The characteristic finding was leukemic cells with highly indented or lobulated flower-like nuclei in peripheral blood and bone marrow. ATL cells were CD2,CD3,CD4,CD25 positive and CD8 negative. No specific chromosome abnormality or HLA type was found. Seven of 8 patients examined had HTLV-Ⅰ antibody. The HTLV-Ⅰ provirus genome sequence integrated into host cell DNA was amplified by PCR and confirmed by liquid hybridization. All of these results showed that HTLV-Ⅰ was also the etiological agent of ATL in China. One of the 9 cases of ATL was classified as lymphoma type, one as chronic-type, and the rest as acute type.

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