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Ketoacidosis is treated with intravascular fluid replacement; an insulin infusion to control the plasma glucose level; possible bicarbonate, potassium, and phosphate administration; and close monitoring of the urine output, serum glucose level, and electrolytes.

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Sodium bicarbonate to alkalinize urine and venoclysis of 5% glucose solution for hydration we...

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Results:Biochemical indicators: the concentrations of K+, Na+ and Cl－ in the serum after the infusion are different with those before the infusion; other indicators don't have the significant difference. The mean infusion time of group A is longer than that of group B (p=0.006), while the dosis letalis of KCl doesn't have significant difference between groups (p=0.062); the concentrations of K+ in blood, Na+, Mg2+ and Cl－ in serum have the significant difference between groups; the urine volume and the concentrations of all the urine electrolyte indicators don't have the statistical significant difference between groups.

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The titration of the sodium hydrogen carbonate content in medicinal sodium bicarbonate tablet was compared with microburette under syringe control made on our own with conventional burette.

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Once the patient is admitted to the hospital, add sodium bicarbonate ampules of 50 mEq/L to each second or third bottle of glucose, so that the pH of the urine is maintained above 6.5 (the usual requirement for bicarbonate is 200–300 mEq/L for the first day).

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