METHODS: Adult male Wistar rats, 9 weeks of age, were injected intraperitoneally with STZ to create diabetes. At 2 week after the models were created, BDNF protein was administered into the vitreous cavities of rats. At 4 week after the models were created, the rats were killed and the retina was removed for Western blotting and Whole-mount immunohistochemistry for TH to observe the changes of TH and dopaminergic amacrine cells in retina.

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Review articles only; calretinin; fovea centralis; macula lutea; ora serrata; photoreceptors; rods; cones; optic tract; optic nerve; visual cortex; color vision; photoreception; opsin; rhodopsin; guanine nucleotide-binding protein; G protein-coupled receptors; ion channels (cyclic GMP-gated); guanylate cyclase; cyclic GMP; dark adaptation; visual pigments; polyenes; 11-cis-retinal; vitamin A; chromophores; arrestin; recoverin; phosducin; transducin; bipolar cells; retinal ganglion cells; retinal progenitor cells; amacrine cells; Mueller cells; light; retinogenesis; ommatidia; optic vesicles; retinitis pigmentosa; blindness; macular degeneration; blind spot; Mach bands; electroretinograms; binocular vision; visual acuity; vision; retina

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Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

結(jié)果檢出10個家系25例病人及1例癥狀前18歲女孩有MJD基因突變，CAG三核苷酸重復(fù)73～79次精品综合自拍第一页，異常等位基因片段長380～402bp人人干97，均為雜合子；正常人CAG三核苷酸重復(fù)18～40次国产真实宾馆嫖妓视频播放，等位片段長200～270bp免费一级性交黄片无码，電生理發(fā)現(xiàn)MJD的SCV減慢比MCV明顯，而下肢的MCV国产91资源小视频、SCV又較上肢明顯一级片免费黄色网站，BAEP、VEP均有不同程度的潛伏期延長或波的異常77777青操网；MJD的父親遺傳早于母親久久精品囯产AV，進(jìn)展也較塊，臨床以小腦性共濟(jì)失調(diào)為突出癥狀一区二区裸体，其次為構(gòu)音障礙九九热最新网址、突眼等，肌肉萎縮僅見于晚期病人欧美日韩中国产视频；MRI示小腦萎縮較明顯国产精品亚洲第一区柳州莫青，腦干萎縮并不嚴(yán)重，未見明顯的頸髓萎縮黄A片免费网站在线播放。

Ve: To observe the curative effect of Yantu Fang for relapse of Graves' disease after hormone treatment.

目的：觀察自擬眼突方治療Graves眼病激素治療后復(fù)發(fā)的療效138福利导航。

Graves' ophthalmopathy is a common autoimmune disorder that display with Graves' disease showing characteristic clinical feature such as proptosis,eyelid retraction and chemosis.

葛瑞夫茲氏眼病變?yōu)榘殡S葛瑞夫茲氏癥常見的自體免疫疾病，其主要臨床癥狀包括眼突免费网禁拗女网站、眼瞼外翻及結(jié)膜水腫乡村妇女毛多水多下口。

4The diameter and length of the clinoid segment of internal carotid artery are 4.02±0.58mm(2.80—5.11mm)and 3.06±0.89(1.07—5.04mm).

5絕大部分眼動脈發(fā)自頸內(nèi)動脈床突上段，占93.75﹪www.69视频，它的直徑為1.52±0.27mm(0.94—1.97mm)爱爱噜噜噜爱爱亚洲。

We introduced improved primary mixed glial culture and different-attachment method to isolate and purify the OPCs, the cells were proliferated in serum-free medium, flow cytometry and immunohischemistry methods were employed to estimate the purity of cultured OPCs. Their abilities of differentiation and expression of trophic factors were identified by RT-PCR and immunostaining. Several methods including TUNEL and MTT were adopted to estimate the protective effects of conditioned culture medium from oligodendrocyte lineage cells on the primary cultured cerebellar granule neurons. Intravitreal transplant of OPCs, combined with retrograde fluorescent labeling the superior colliculus and intraorbital optic nerve transection, were used to investigate the protective effects of OPCs on the axotomized RGCs in vivo. Intravitreal transplantof OPCs or NSCs on the newborn rats, and retinal transplant of OPCs on the young rats were performed, to observe the myelin formation in the retina at different stages after cellular transplantation. Optic nerve transection was carried out on some rats with myelinated retinae, to study the influence of myelination on the injuried RGCs.

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Data were analyzed from photographs from optical microscopy and Computer Image Analysis.Results:Gene expression level of bcl-2mRNA (numeric density and concentration of bcl-2 immunopositive neurons) in layer Ⅲ of the ipsilateral visual cortex area 17 and the laminas receiving ipsilateral geniculate input from the strabismic and deprived eyes are significantly lower than the input from the untreated eyes.

MS1和MD1組幼貓實(shí)驗(yàn)眼同側(cè)視皮質(zhì)17區(qū)Ⅳ層及同側(cè)外側(cè)膝狀體Al層神經(jīng)元在視覺發(fā)育敏感期內(nèi)亚洲精品综合玖玖爱在线，由于長期的斜視及形覺剝奪效應(yīng)以致功能低下，對Bcl-2調(diào)節(jié)的敏感性降低国产在线3p，以及對NTs的營養(yǎng)保護(hù)及上調(diào)Bcl-2 mRNA表達(dá)水平應(yīng)答能力降低人人骚人人操人人高潮，在雙眼競爭的神經(jīng)元發(fā)育及突觸連接中處于劣勢，使對側(cè)眼形成優(yōu)勢循環(huán)岛国欧美黄色网站视频。

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