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Results l.Serum concentrations of VCAM-1 in PIH (93.39 + 57.3)ug/ml were higher than that in normal pregnant group. Serum concentrations of VCAM-1 in moderate(97.89 + 34.07)ug/ml and severe PIH(132.24 + 60.97)ug/ml were significantly higher than that in normal group.(P.05, P.01). There was no difference between serum levels of VCAM-1 mild PIH and normal pregnant group. 2.Serum levels of IL-6 in PIH group(102.17 ?48. 31)pg/ml were significantly higher than that in normal group(49.16 + 12.9)pg/ml.Serum levels of IL-6 in moderate(95.79+31.19)pg/ml and severe PIH( 127.27+11.3 8)pg,ml were significantly higher than that in normal group. There was no difference between serum levels of PIH in mild PIH (52.13 + 12.90)pg/ml and normal pregnant group. 3. In PIH group, serum concentrations of VCAM-1 correlate with the levels of IL-6,r=0.63. 4.The expression of VCAM-1 in cytotrophoblast of spiral arteries in normal pregnant group(100%) were significantly higher than that in PIH group.Theexpression of VCAM-1 in moderate PIH(37.50%) and sever PIH were lower than that in normal group.There was no difference between the mild PIH and normal group.Conclusions The increased levels of serum of VCAM-1 may participate in the process of vascular endothelium damages in PIH.

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Therelationship between the turbulent kinetic energy and its dissipation rate,whichis widely used to parameterize the dissipation rate in turbulence closure models,is found to hold well for both reversing and rotating flows,but with differentcoefficients.Microstructure profiling measurements at two comparative stations (a deepercentral basin and a local shelf break) in the stratified Yellow Sea are analyzed,with emphasis on tidal and internal-wave induced turbulence near the bottomand in the pyenocline.The water column has a distinct three-layer thermohaline structure,consisting of weakly stratified surface and bottom boundary layers anda narrow sharp pycnocline.Turbulence in the surface layer is controlled by thediurnal cycle of buoyancy flux and wind forcing at the sea surface.while thebottom stress induced by barotropic tidal eurrents dominates turbulence in thebottom boundary layer.The maximum level at which the tidally enhanced mixingcan affect generally depends on the magnitude of the tidal current,and it canbe up to 10-15 m in the Yellow Sea.This suggests that,in the deeper regionsof the shelf seas,turbulent dissipation and mixing are very weak at the levelsbetween the near-bottom tidally enhanced layer and the pycnocline.Therefore,these levels provide a significant bottle neck for the vertical exchanges.In theshallow regions,however,the tidally-induced turbulence can occupy the wholewater colum below the pycnocline.A quarter-diurnal periodicities of the turbulentdissipation rate and eddy diffusivity are found at different heights with evidenttime lag.In the relatively flat central basin,the pycnocline is essentially non-turbulent and internal-wave activity is very weak.Therefore,vertical fluxes acrossthe pycnocline decreased to molecular levels.In contrast,internal waves of variousperiods can be always found near the local shelf break.

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